Cadmium

tumor protein p53 ; Homo sapiens







52 Article(s)
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1 35088369 Activation of multiple proteolysis systems contributes to acute cadmium cytotoxicity. 2022 Mar 1
2 33078306 Long Non-coding RNA Expression Profile in Broiler Liver with Cadmium-Induced Oxidative Damage. 2021 Aug 1
3 33321290 Autophagy-mediated cytoplasmic accumulation of p53 leads to apoptosis through DRAM-BAX in cadmium-exposed human proximal tubular cells. 2021 Jan 1 7
4 33803748 Combining Patulin with Cadmium Induces Enhanced Hepatotoxicity and Nephrotoxicity In Vitro and In Vivo. 2021 Mar 18 1
5 31738976 Neuronal specific and non-specific responses to cadmium possibly involved in neurodegeneration: A toxicogenomics study in a human neuronal cell model. 2020 Jan 1
6 31904905 Influence of silica nanoparticles on cadmium-induced cytotoxicity, oxidative stress, and apoptosis in human liver HepG2 cells. 2020 May 1
7 31942711 TiO2 nanoparticles potentiated the cytotoxicity, oxidative stress and apoptosis response of cadmium in two different human cells. 2020 Apr 1
8 32065645 Expression of Concern: "Cadmium Induces Intracellular Ca2+- and H2O2-Dependent Apoptosis through JNK- and p53-Mediated Pathways in Skin Epidermal Cell line". 2020 May 1 1
9 32872665 16-Hydroxycleroda-3,13-dien-15,16-olide Induces Apoptosis in Human Bladder Cancer Cells through Cell Cycle Arrest, Mitochondria ROS Overproduction, and Inactivation of EGFR-Related Signalling Pathways. 2020 Aug 30 1
10 33497945 Inhibition of ROS/NLRP3/Caspase-1 mediated pyroptosis attenuates cadmium-induced apoptosis in duck renal tubular epithelial cells. 2020 Oct 23 2
11 30388553 CdS nanocrystals/graphene oxide-AuNPs based electrochemiluminescence immunosensor in sensitive quantification of a cancer biomarker: p53. 2019 Feb 1 4
12 30537571 Cadmium induces apoptotic program imbalance and cell cycle inhibitor expression in cultured human astrocytes. 2019 Jan 1
13 31239671 In vitro cytotoxicity and transfection efficiency of pDNA encoded p53 gene-loaded chitosan-sodium deoxycholate nanoparticles. 2019 2
14 28102315 Methyl-Cytosine-Driven Structural Changes Enhance Adduction Kinetics of an Exon 7 fragment of the p53 Gene. 2017 Jan 19 1
15 30460048 Cell specific stress responses of cadmium-induced cytotoxicity. 2017 4
16 26912277 Accumulation of p53 via down-regulation of UBE2D family genes is a critical pathway for cadmium-induced renal toxicity. 2016 Feb 25 6
17 26977261 Different Regulation of p53 Expression by Cadmium Exposure in Kidney, Liver, Intestine, Vasculature, and Brain Astrocytes. 2016 Jan 5
18 27620489 Heme oxygenase-1-mediated apoptosis under cadmium-induced oxidative stress is regulated by autophagy, which is sensitized by tumor suppressor p53. 2016 Oct 7 8
19 25446071 Impact of cadmium, cobalt and nickel on sequence-specific DNA binding of p63 and p73 in vitro and in cells. 2015 Jan 2 8
20 25490952 Cadmium-induced embryopathy: nitric oxide rescues teratogenic effects of cadmium. 2015 Mar 1
21 26519823 Cadmium treatment suppresses DNA polymerase δ catalytic subunit gene expression by acting on the p53 and Sp1 regulatory axis. 2015 Nov 2
22 24491565 Cadmium induces cytotoxicity in human bronchial epithelial cells through upregulation of eIF5A1 and NF-kappaB. 2014 Feb 28 2
23 25101185 Cadmium Impairs p53 Activity in HepG2 Cells. 2014 2
24 25118938 Detrimental effects of Notch1 signaling activated by cadmium in renal proximal tubular epithelial cells. 2014 Aug 14 1
25 23405080 Cadmium induces apoptosis in pancreatic β-cells through a mitochondria-dependent pathway: the role of oxidative stress-mediated c-Jun N-terminal kinase activation. 2013 1
26 24100270 Mechanism of cadmium induced apoptosis in human peripheral blood lymphocytes: the role of p53, Fas and Caspase-3. 2013 Nov 2
27 21605570 Impact of cadmium on hOGG1 and APE1 as a function of the cellular p53 status. 2012 Aug 1 5
28 22448262 Cadmium induces p53-dependent apoptosis in human prostate epithelial cells. 2012 8
29 23652223 Rising environmental cadmium levels in developing countries: threat to genome stability and health. 2012 Dec 18 3
30 20839231 Involvement of E2F1 transcriptional activity in cadmium-induced cell-cycle arrest at G1 in human lung fibroblasts. 2011 Mar 2
31 20390439 Mechanisms in cadmium-induced carcinogenicity: recent insights. 2010 Oct 1
32 18781628 Oxidation of methionine residue at hydrophobic core destabilizes p53 tetrameric structure. 2009 Jan 1
33 19475715 Divergence to apoptosis from ROS induced cell cycle arrest: effect of cadmium. 2009 Apr 26 1
34 17610031 Cadmium induces mitochondria-dependent apoptosis of normal human hepatocytes. 2008 Jan 2
35 18281164 Mechanism of cadmium induced apoptosis in the immunocyte. 2008 Mar 15 3
36 18297607 Characterization of the cell death induced by cadmium in HaCaT and C6 cell lines. 2008 Feb 2
37 17174997 p53-Dependent but ATM-independent inhibition of DNA synthesis and G2 arrest in cadmium-treated human fibroblasts. 2007 Jan 15 8
38 17514353 Calcium-mediated activation of PI3K and p53 leads to apoptosis in thyroid carcinoma cells. 2007 Jun 1
39 16300733 Recognition of cisplatin-damaged DNA by p53 protein: critical role of the p53 C-terminal domain. 2006 Jan 13 1
40 15025498 Effects of cadmium(II) on (+/-)-anti-benzo[a]pyrene-7,8-diol-9,10-epoxide-induced DNA damage response in human fibroblasts and DNA repair: a possible mechanism of cadmium's cogenotoxicity. 2004 Mar 2
41 15450950 Cadmium induces apoptotic cell death in WI 38 cells via caspase-dependent Bid cleavage and calpain-mediated mitochondrial Bax cleavage by Bcl-2-independent pathway. 2004 Nov 1 1
42 15515126 Suicide gene therapy with an adenovirus expressing the fusion gene CD::UPRT in human glioblastomas: different sensitivities correlate with p53 status. 2004 Dec 1
43 11917017 Factors governing loss and rescue of DNA binding upon single and double mutations in the p53 core domain. 2002 Apr 1 1
44 11956312 Loss of heterochromatin protein 1 (HP1) chromodomain function in mammalian cells by intracellular antibodies causes cell death. 2002 May 1 1
45 11991084 Cadmium-induced apoptosis of primary epithelial lung cells: involvement of Bax and p53, but not of oxidative stress. 2002 1
46 11302731 Cadmium induces phosphorylation of p53 at serine 15 in MCF-7 cells. 2001 Apr 20 2
47 11594760 p53 unfolding detected by CD but not by tryptophan fluorescence. 2001 Oct 19 1
48 10799339 Cadmium induces c-myc, p53, and c-jun expression in normal human prostate epithelial cells as a prelude to apoptosis. 2000 May 1 2
49 10531375 Cadmium induces conformational modifications of wild-type p53 and suppresses p53 response to DNA damage in cultured cells. 1999 Oct 29 7
50 10604188 Metal ions as regulators of the conformation and function of the tumour suppressor protein p53: implications for carcinogenesis. 1999 Aug 2