Pub. Date : 2013
PMID : 23405080
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Cd also increased intracellular reactive oxygen species (ROS) generation and malondialdehyde (MDA) production and induced mitochondrial dysfunction (the loss of mitochondrial membrane potential (MMP) and the increase of cytosolic cytochrome c release), the decreased Bcl-2 expression, increased p53 expression, poly (ADP-ribose) polymerase (PARP) cleavage, and caspase cascades, which accompanied with intracellular Cd accumulation. | Cadmium | tumor protein p53 | Homo sapiens |