GSK2830371

tumor protein p53 ; Homo sapiens







9 Article(s)
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PMID
Title
Pub. Year
#Total Relationships
1 34359777 WIP1 Inhibition by GSK2830371 Potentiates HDM201 through Enhanced p53 Phosphorylation and Activation in Liver Adenocarcinoma Cells. 2021 Jul 31 6
2 29235570 Targeting negative regulation of p53 by MDM2 and WIP1 as a therapeutic strategy in cutaneous melanoma. 2018 Feb 20 5
3 30045945 Genome-scale CRISPR-Cas9 screen identifies druggable dependencies in TP53 wild-type Ewing sarcoma. 2018 Aug 6 1
4 26832796 Chemical Inhibition of Wild-Type p53-Induced Phosphatase 1 (WIP1/PPM1D) by GSK2830371 Potentiates the Sensitivity to MDM2 Inhibitors in a p53-Dependent Manner. 2016 Mar 2
5 26883108 Inhibition of WIP1 phosphatase sensitizes breast cancer cells to genotoxic stress and to MDM2 antagonist nutlin-3. 2016 Mar 22 2
6 27183917 Cooperation of Nutlin-3a and a Wip1 inhibitor to induce p53 activity. 2016 May 31 1
7 27626308 The pathophysiological significance of PPM1D and therapeutic targeting of PPM1D-mediated signaling by GSK2830371 in mantle cell lymphoma. 2016 Oct 25 5
8 27991505 Wip1 inhibitor GSK2830371 inhibits neuroblastoma growth by inducing Chk2/p53-mediated apoptosis. 2016 Dec 19 7
9 25658463 WIP1 phosphatase as a potential therapeutic target in neuroblastoma. 2015 3