| 1 |
31645443 | Ceramide-Rubusoside Nanomicelles, a Potential Therapeutic Approach to Target Cancers Carrying p53 Missense Mutations. | 2020 Feb |
2 |
| 2 |
32767230 | Crosstalk between Noxa, Bcl-2, and ceramide in mediating p53-dependent apoptosis in Molt-4 human T-cell leukemia. | 2020 Dec |
7 |
| 3 |
32973966 | Small ceramide tames big p53 mutant beast. | 2020 Sep 15 |
1 |
| 4 |
33205006 | Gb3-cSrc complex in glycosphingolipid-enriched microdomains contributes to the expression of p53 mutant protein and cancer drug resistance via β-catenin-activated RNA methylation. | 2020 Nov |
3 |
| 5 |
30578766 | An N6-methyladenosine at the transited codon 273 of p53 pre-mRNA promotes the expression of R273H mutant protein and drug resistance of cancer cells. | 2019 Feb |
5 |
| 6 |
31480728 | C2-Ceramide-Induced Rb-Dominant Senescence-Like Phenotype Leads to Human Breast Cancer MCF-7 Escape from p53-Dependent Cell Death. | 2019 Sep 2 |
2 |
| 7 |
29229990 | Tumor suppressor p53 links ceramide metabolism to DNA damage response through alkaline ceramidase 2. | 2018 May |
2 |
| 8 |
30059758 | Chemosensitivity of human colon cancer cells is influenced by a p53-dependent enhancement of ceramide synthase 5 and induction of autophagy. | 2018 Oct |
4 |
| 9 |
30060809 | Ceramide Signaling and p53 Pathways. | 2018 |
7 |
| 10 |
30297838 | C16-ceramide is a natural regulatory ligand of p53 in cellular stress response. | 2018 Oct 8 |
2 |
| 11 |
29272311 | Genomic alterations during p53-dependent apoptosis induced by γ-irradiation of Molt-4 leukemia cells. | 2017 |
1 |
| 12 |
27302066 | CerS6 Is a Novel Transcriptional Target of p53 Protein Activated by Non-genotoxic Stress. | 2016 Aug 5 |
1 |
| 13 |
27517620 | Inhibition of glucosylceramide synthase eliminates the oncogenic function of p53 R273H mutant in the epithelial-mesenchymal transition and induced pluripotency of colon cancer cells. | 2016 Sep 13 |
2 |
| 14 |
25797839 | Proteomic analysis of human glioblastoma cell lines differently resistant to a nitric oxide releasing agent. | 2015 Jun |
1 |
| 15 |
26116623 | C6 ceramide dramatically increases vincristine sensitivity both in vivo and in vitro, involving AMP-activated protein kinase-p53 signaling. | 2015 Sep |
1 |
| 16 |
26446704 | Activated PKR inhibits pancreatic β-cell proliferation through sumoylation-dependent stabilization of P53. | 2015 Dec |
2 |
| 17 |
25195822 | Ceramide modulates pre-mRNA splicing to restore the expression of wild-type tumor suppressor p53 in deletion-mutant cancer cells. | 2014 Nov |
5 |
| 18 |
23290777 | Ceramide glycosylation catalyzed by glucosylceramide synthase and cancer drug resistance. | 2013 |
1 |
| 19 |
23455468 | p53 and Ceramide as Collaborators in the Stress Response. | 2013 Mar 1 |
4 |
| 20 |
23495037 | Mechanisms of ceramide-induced COX-2-dependent apoptosis in human ovarian cancer OVCAR-3 cells partially overlapped with resveratrol. | 2013 Aug |
4 |
| 21 |
23530619 | p53-independent early and late apoptosis is mediated by ceramide after exposure of tumor cells to photon or carbon ion irradiation. | 2013 Mar 25 |
3 |
| 22 |
24269881 | Metformin limits ceramide-induced senescence in C2C12 myoblasts. | 2013 Nov-Dec |
2 |
| 23 |
22349266 | DNA damage induces down-regulation of UDP-glucose ceramide glucosyltransferase, increases ceramide levels and triggers apoptosis in p53-deficient cancer cells. | 2012 Jul |
3 |
| 24 |
24319543 | C-6 Ceramide Induces p53 Dependent Apoptosis in Human Astrocytoma Grade4 (Glioblastoma Multiforme) Cells. | 2012 Feb 1 |
1 |
| 25 |
21035490 | p53 and regulation of bioactive sphingolipids. | 2011 |
2 |
| 26 |
21278235 | Suppression of glucosylceramide synthase restores p53-dependent apoptosis in mutant p53 cancer cells. | 2011 Mar 15 |
3 |
| 27 |
21972148 | Resuscitating wild-type p53 expression by disrupting ceramide glycosylation: a novel approach to target mutant p53 tumors. | 2011 Oct 15 |
5 |
| 28 |
20514393 | Inhibition of p53 sensitizes MCF-7 cells to ceramide treatment. | 2010 Jul |
5 |
| 29 |
18204081 | PPP1CA contributes to the senescence program induced by oncogenic Ras. | 2008 Mar |
1 |
| 30 |
18400537 | De novo N-palmitoylsphingosine synthesis is the major biochemical mechanism of ceramide accumulation following p53 up-regulation. | 2008 Jun |
7 |
| 31 |
16297852 | Bcl-2 but not clusterin/apolipoprotein J protected human diploid fibroblasts and immortalized keratinocytes from ceramide-induced apoptosis: role of p53 in the ceramide response. | 2006 Jan 1 |
2 |
| 32 |
16510697 | Potent antitumor activity of a novel cationic pyridinium-ceramide alone or in combination with gemcitabine against human head and neck squamous cell carcinomas in vitro and in vivo. | 2006 Jun |
1 |
| 33 |
15013522 | Ceramide synthesis and metabolism as a target for cancer therapy. | 2004 Apr 8 |
1 |
| 34 |
15088070 | p53-Independent ceramide formation in human glioma cells during gamma-radiation-induced apoptosis. | 2004 Aug |
6 |
| 35 |
15131591 | Molecular mechanisms of TNF-alpha-induced ceramide formation in human glioma cells: P53-mediated oxidant stress-dependent and -independent pathways. | 2004 Sep |
4 |
| 36 |
15201971 | Ceramide triggers caspase activation during gamma-radiation-induced apoptosis of human glioma cells lacking functional p53. | 2004 Jul |
4 |
| 37 |
12967322 | Ceramide and glutathione define two independently regulated pathways of cell death initiated by p53 in Molt-4 leukaemia cells. | 2003 Dec 15 |
2 |
| 38 |
11822871 | Acid sphingomyelinase activation requires caspase-8 but not p53 nor reactive oxygen species during Fas-induced apoptosis in human glioma cells. | 2002 Feb 15 |
2 |
| 39 |
11915341 | [Involvement of p53 in ceramide signaling cascade]. | 2002 Mar |
1 |
| 40 |
11960374 | P53 mediates ceramide-induced apoptosis in SKN-SH cells. | 2002 Mar 27 |
4 |
| 41 |
12011072 | Clustering of CD40 ligand is required to form a functional contact with CD40. | 2002 Aug 16 |
1 |
| 42 |
11313880 | p53 regulates ceramide formation by neutral sphingomyelinase through reactive oxygen species in human glioma cells. | 2001 Mar 15 |
7 |
| 43 |
11820739 | Distinct apoptotic phenotypes induced by radiation and ceramide in both p53-wild-type and p53-mutated lymphoblastoid cells. | 2001 Dec |
4 |
| 44 |
10745271 | Ceramide-induced cell death is independent of the Fas/Fas ligand pathway and is prevented by Nur77 overexpression in A20 B cells. | 2000 Mar |
2 |
| 45 |
10874474 | Induction of p53-independent p21 during ceramide-induced G1 arrest in human hepatocarcinoma cells. | 2000 |
3 |
| 46 |
11106681 | Synergistic cytotoxicity in solid tumor cell lines between N-(4-hydroxyphenyl)retinamide and modulators of ceramide metabolism. | 2000 Dec 6 |
1 |
| 47 |
11324420 | Apoptosis induced by ceramide in hepatocellular carcinoma Bel7402 cells. | 2000 Mar |
1 |
| 48 |
10360645 | Ceramide triggers p53-dependent apoptosis in genetically defined fibrosarcoma tumour cells. | 1999 May |
3 |
| 49 |
10393722 | Increase of ceramide and induction of mixed apoptosis/necrosis by N-(4-hydroxyphenyl)- retinamide in neuroblastoma cell lines. | 1999 Jul 7 |
1 |
| 50 |
10585263 | p21 promotes ceramide-induced apoptosis and antagonizes the antideath effect of Bcl-2 in human hepatocarcinoma cells. | 1999 Dec 15 |
1 |