Pub. Date : 2018
PMID : 30060809
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Ceramides, important players in signal transduction, interact with multiple cellular pathways, including p53 pathways. | Ceramides | tumor protein p53 | Homo sapiens |
| 2 | However, the relationship between ceramide and p53 is very complex, and mechanisms underlying their coregulation are diverse and not fully characterized. | Ceramides | tumor protein p53 | Homo sapiens |
| 3 | We discuss the recent studies, which underscore the function of p53 in the regulation of ceramide pathways and the reciprocal regulation of p53 by ceramide. | Ceramides | tumor protein p53 | Homo sapiens |
| 4 | We discuss the recent studies, which underscore the function of p53 in the regulation of ceramide pathways and the reciprocal regulation of p53 by ceramide. | Ceramides | tumor protein p53 | Homo sapiens |
| 5 | This complex relationship is based on several molecular mechanisms including the p53-dependent transcriptional regulation of enzymes in sphingolipid pathways, the activation of mutant p53 through ceramide-mediated alternative splicing, as well as modulation of the p53 function through direct and indirect effects on p53 coregulators and downstream targets. | Ceramides | tumor protein p53 | Homo sapiens |
| 6 | This complex relationship is based on several molecular mechanisms including the p53-dependent transcriptional regulation of enzymes in sphingolipid pathways, the activation of mutant p53 through ceramide-mediated alternative splicing, as well as modulation of the p53 function through direct and indirect effects on p53 coregulators and downstream targets. | Ceramides | tumor protein p53 | Homo sapiens |
| 7 | This complex relationship is based on several molecular mechanisms including the p53-dependent transcriptional regulation of enzymes in sphingolipid pathways, the activation of mutant p53 through ceramide-mediated alternative splicing, as well as modulation of the p53 function through direct and indirect effects on p53 coregulators and downstream targets. | Ceramides | tumor protein p53 | Homo sapiens |