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16518418 | Potentiation of irinotecan sensitivity by Se-methylselenocysteine in an in vivo tumor model is associated with downregulation of cyclooxygenase-2, inducible nitric oxide synthase, and hypoxia-inducible factor 1alpha expression, resulting in reduced angiogenesis. | 2006 Apr 20 |
2 |
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16204068 | Effect of p53 status and STAT1 on chemotherapy-induced, Fas-mediated apoptosis in colorectal cancer. | 2005 Oct 1 |
6 |
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14961077 | p53 disruption profoundly alters the response of human glioblastoma cells to DNA topoisomerase I inhibition. | 2004 Feb 12 |
3 |
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15001986 | Enhanced sensitivity to irinotecan by Cdk1 inhibition in the p53-deficient HT29 human colon cancer cell line. | 2004 Mar 4 |
6 |
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15041737 | Characterization of p53 wild-type and null isogenic colorectal cancer cell lines resistant to 5-fluorouracil, oxaliplatin, and irinotecan. | 2004 Mar 15 |
1 |
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15143945 | Effect of human noxa on irinotecan-induced apoptosis in human gastric carcinoma cell lines. | 2004 May-Jun |
1 |
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15213307 | Enhanced 7-ethyl-10-hydroxycamptothecin (SN-38) lethality by methylselenocysteine is associated with Chk2 phosphorylation at threonine-68 and down-regulation of Cdc6 expression. | 2004 Jul |
2 |
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15374978 | Potentiation of cytotoxicity of topoisomerase i poison by concurrent and sequential treatment with the checkpoint inhibitor UCN-01 involves disparate mechanisms resulting in either p53-independent clonogenic suppression or p53-dependent mitotic catastrophe. | 2004 Sep 15 |
1 |
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15604280 | Elimination of hepatic metastases of colon cancer cells via p53-independent cross-talk between irinotecan and Apo2 ligand/TRAIL. | 2004 Dec 15 |
14 |
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12538824 | p53-mediated regulation of expression of a rabbit liver carboxylesterase confers sensitivity to 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin (CPT-11). | 2003 Feb |
6 |
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14645705 | Requirement of p53 targets in chemosensitization of colonic carcinoma to death ligand therapy. | 2003 Dec 9 |
1 |
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11894120 | Antisense anti-MDM2 mixed-backbone oligonucleotides enhance therapeutic efficacy of topoisomerase I inhibitor irinotecan in nude mice bearing human cancer xenografts: In vivo activity and mechanisms. | 2002 Apr |
1 |
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12209584 | Cellular effects of CPT-11 on colon carcinoma cells: dependence on p53 and hMLH1 status. | 2002 Sep 1 |
1 |
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10732766 | Sensitivity to CPT-11 of xenografted human colorectal cancers as a function of microsatellite instability and p53 status. | 2000 Feb |
2 |
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10770640 | Alteration of drug chemosensitivity caused by the adenovirus-mediated transfer of the wild-type p53 gene in human lung cancer cells. | 2000 Feb |
1 |
| 66 |
10604724 | Schedule-dependent cytotoxicity of SN-38 in p53 wild-type and mutant colon adenocarcinoma cell lines. | 1999 Dec |
4 |
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9506540 | Acute overexpression of wt p53 facilitates anticancer drug-induced death of cancer and normal cells. | 1998 Mar 16 |
1 |
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9743293 | Induction of p53-dependent and p53-independent cellular responses by topoisomerase 1 inhibitors. | 1998 Sep |
1 |