Staurosporine

tumor protein p53 ; Homo sapiens







28 Article(s)
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1 34878630 Exploring the MEN1 dependent modulation of caspase 8 and caspase 3 in human pancreatic and murine embryo fibroblast cells. 2022 Feb 1
2 30774867 The anti-apoptotic proteins NAF-1 and iASPP interact to drive apoptosis in cancer cells. 2019 Jan 21 1
3 24128664 Increased susceptibility to apoptosis in cultured fibroblasts from antipsychotic-naïve first-episode schizophrenia patients. 2014 Jan 1
4 25036040 Integrating genomics and proteomics data to predict drug effects using binary linear programming. 2014 1
5 22184125 α-Secretase-derived fragment of cellular prion, N1, protects against monomeric and oligomeric amyloid β (Aβ)-associated cell death. 2012 Feb 10 1
6 22484386 Mood stabilizers commonly restore staurosporine-induced increase of p53 expression and following decrease of Bcl-2 expression in SH-SY5Y cells. 2012 Aug 7 1
7 19880522 Pyk2 inhibition of p53 as an adaptive and intrinsic mechanism facilitating cell proliferation and survival. 2010 Jan 15 1
8 20810912 Hypoxia downregulates p53 but induces apoptosis and enhances expression of BAD in cultures of human syncytiotrophoblasts. 2010 Nov 1
9 19216720 Spatiotemporal activation of caspase-dependent and -independent pathways in staurosporine-induced apoptosis of p53wt and p53mt human cervical carcinoma cells. 2009 Jun 4 6
10 19857493 Role of p53/FAK association and p53Ser46 phosphorylation in staurosporine-mediated apoptosis: wild type versus mutant p53-R175H. 2009 Nov 19 2
11 18405662 TMP21 regulates Abeta production but does not affect caspase-3, p53, and neprilysin. 2008 Jun 20 1
12 17121821 The C-terminal products of cellular prion protein processing, C1 and C2, exert distinct influence on p53-dependent staurosporine-induced caspase-3 activation. 2007 Jan 19 2
13 17276981 p53-Dependent Aph-1 and Pen-2 anti-apoptotic phenotype requires the integrity of the gamma-secretase complex but is independent of its activity. 2007 Apr 6 1
14 17726646 Functional implications of caspase-mediated RhoGDI2 processing during apoptosis of HL60 and K562 leukemia cells. 2007 Nov 1
15 18088187 p53-dependent Chk1 phosphorylation is required for maintenance of prolonged G2 Arrest. 2007 Dec 2
16 16514420 Neural precursor cells possess multiple p53-dependent apoptotic pathways. 2006 Oct 1
17 16554962 Modulation of p53 transcriptional activity by PRIMA-1 and Pifithrin-alpha on staurosporine-induced apoptosis of wild-type and mutated p53 epithelial cells. 2006 May 4
18 16827139 P53 mutants suppress ZBP-89 function. 2006 May-Jun 1
19 15474986 p53 protein activates the transcription of human proliferating cell nuclear antigen in response to 4-nitroquinoline N-oxide treatment. 2005 Feb 2
20 15258465 Mitochondrial translocation of p53 and mitochondrial membrane potential (Delta Psi m) dissipation are early events in staurosporine-induced apoptosis of wild type and mutated p53 epithelial cells. 2004 May 2
21 15339383 Involvement of cyclin dependent kinase 5 and its activator p35 in staurosporine-induced apoptosis of cortical neurons. 2004 Sep 1
22 15498771 Preapoptotic chromatin condensation upstream of the mitochondrial checkpoint. 2004 Dec 31 2
23 12556443 The C-terminal fragment of presenilin 2 triggers p53-mediated staurosporine-induced apoptosis, a function independent of the presenilinase-derived N-terminal counterpart. 2003 Apr 4 1
24 11299740 Abrogation of G2 checkpoint specifically sensitize p53 defective cells to cancer chemotherapeutic agents. 2001 Jan-Feb 1
25 11313973 Mechanism of hyperploid cell formation induced by microtubule inhibiting drug in glioma cell lines. 2001 Jan 25 1
26 10518116 Differential effects of staurosporine and retinoic acid on the vulnerability of the SH-SY5Y neuroblastoma cells: involvement of bcl-2 and p53 proteins. 1999 Nov 1 3
27 10698260 Both low and high concentrations of staurosporine induce G1 arrest through down-regulation of cyclin E and cdk2 expression. 1999 Dec 1
28 9484835 U.V.C.-induction of p53 activation and accumulation is dependent on cell cycle and pathways involving protein synthesis and phosphorylation. 1998 Jan 29 3