Title : Involvement of cyclin dependent kinase 5 and its activator p35 in staurosporine-induced apoptosis of cortical neurons.

Pub. Date : 2004 Sep

PMID : 15339383






1 Functional Relationships(s)
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1 The protein level of Cdk4 protein increased at 3 h and then decreased gradually from 6 h, but it was still higher than that in the vehicle cultures at 12 h. The p53 level decreased obviously at 3 h after staurosporine treatment and then seemed to increase at 12 h, but remained lower than that of vehicle cultures. Staurosporine tumor protein p53 Homo sapiens