Azacitidine

tumor protein p53 ; Homo sapiens







36 Article(s)
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1 34854834 Targeting the cluster of differentiation 47/signal-regulatory protein alpha axis in myeloid malignancies. 2022 Jan 1 1
2 35216478 Emerging Targeted Therapy for Specific Genomic Abnormalities in Acute Myeloid Leukemia. 2022 Feb 21 1
3 35368106 Outcomes of second allogeneic stem cell transplantation and anti-relapse strategies in patients with relapsed/refractory acute myeloid leukemia: A unicentric retrospective analysis. 2022 Apr 3 1
4 35576022 Selinexor synergizes with azacitidine to eliminate myelodysplastic syndrome cells through p53 nuclear accumulation. 2022 May 16 1
5 33449813 Eprenetapopt (APR-246) and Azacitidine in TP53-Mutant Myelodysplastic Syndromes. 2021 May 10 2
6 33600210 Eprenetapopt Plus Azacitidine in TP53-Mutated Myelodysplastic Syndromes and Acute Myeloid Leukemia: A Phase II Study by the Groupe Francophone des Myélodysplasies (GFM). 2021 May 10 5
7 34070172 The Mutational Landscape of Acute Myeloid Leukaemia Predicts Responses and Outcomes in Elderly Patients from the PETHEMA-FLUGAZA Phase 3 Clinical Trial. 2021 May 18 1
8 34405020 The Differential Antitumor Activity of 5-Aza-2'-deoxycytidine in Prostate Cancer DU145, 22RV1, and LNCaP Cells. 2021 2
9 34768330 Lymphocytic Infiltrate and p53 Protein Expression as Predictive Markers of Response and Outcome in Myelodysplastic Syndromes Treated with Azacitidine. 2021 Oct 20 2
10 31488557 Synergistic effects of PRIMA-1Met (APR-246) and 5-azacitidine in TP53-mutated myelodysplastic syndromes and acute myeloid leukemia. 2020 Jun 4
11 31990086 Clonal selection in therapy-related myelodysplastic syndromes and acute myeloid leukemia under azacitidine treatment. 2020 May 2
12 32482751 To target the untargetable: elucidation of synergy of APR-246 and azacitidine in TP53 mutant myelodysplastic syndromes and acute myeloid leukemia. 2020 Jun 1
13 33001991 Impact of TP53 mutations in acute myeloid leukemia patients treated with azacitidine. 2020 4
14 30728460 Derepression of LOXL4 inhibits liver cancer growth by reactivating compromised p53. 2019 Nov 3
15 31048321 Targeting Mitochondrial Structure Sensitizes Acute Myeloid Leukemia to Venetoclax Treatment. 2019 Jul 1
16 29648492 Azacitidine effectively reduces TP53-mutant leukemic cell burden in secondary acute myeloid leukemia after cord blood transplantation. 2018 Nov 1
17 27029827 Pax5 Re-expression in H460 Cells Treated with the Combination of Demethylating Agent and Histone Deacetylase Inhibitor is Associated with the Enhancement of P53 Binding to Pax5 Promoter Region. 2017 3
18 28476801 Azacytidine-induced Chemosensitivity to Doxorubicin in Human Breast Cancer MCF7 Cells. 2017 May 2
19 28484169 Current diagnosis and treatment for myelodysplastc syndromes. 2017 1
20 28505595 Epigenetic drug combination induces remission in mouse xenograft models of pediatric acute myeloid leukemia. 2017 Jul 4
21 28802167 Induction of senescence in cancer cells by 5'-Aza-2'-deoxycytidine: Bioinformatics and experimental insights to its targets. 2017 Oct 1
22 28916527 Demethylation Therapy as a Targeted Treatment for Human Papillomavirus-Associated Head and Neck Cancer. 2017 Dec 1 2
23 29143344 Down-regulation of p16 and MGMT promotes the anti-proliferative and pro-apoptotic effects of 5-Aza-dC and radiation on cervical cancer cells. 2017 Dec 1
24 26651421 A new prognostic index to make short-term prognoses in MDS patients treated with azacitidine: A combination of p53 expression and cytogenetics. 2016 Feb 3
25 25934763 Correction to "5-aza-Cytidine Is a Potent Inhibitor of DNA Methyltransferase 3a and Induces Apoptosis in HCT-116 Colon Cancer Cells via Gadd45- and p53-Dependent Mechanisms". 2015 Jun 1
26 24836762 Prognostic value of TP53 gene mutations in myelodysplastic syndromes and acute myeloid leukemia treated with azacitidine. 2014 Jul 4
27 25134538 TAp73 and ΔNp73 have opposing roles in 5-aza-2'-deoxycytidine-induced apoptosis in breast cancer cells. 2014 Aug 2
28 23924947 Differential induction of apoptosis and senescence by the DNA methyltransferase inhibitors 5-azacytidine and 5-aza-2'-deoxycytidine in solid tumor cells. 2013 Oct 2
29 24319226 Key clinical observations after 5-azacytidine and decitabine treatment of myelodysplastic syndromes suggest practical solutions for better outcomes. 2013 2
30 22893484 Concomitant inhibition of DNA methyltransferase and BCL-2 protein function synergistically induce mitochondrial apoptosis in acute myelogenous leukemia cells. 2012 Dec 1
31 23300844 Acute hypersensitivity of pluripotent testicular cancer-derived embryonal carcinoma to low-dose 5-aza deoxycytidine is associated with global DNA Damage-associated p53 activation, anti-pluripotency and DNA demethylation. 2012 5
32 21903246 The regulation of MASPIN expression in epithelial ovarian cancer: association with p53 status, and MASPIN promoter methylation: a gynecologic oncology group study. 2011 Nov 3
33 19531575 Epigenetic mechanisms of irinotecan sensitivity in colorectal cancer cell lines. 2009 Jul 5
34 15547111 5-Aza-cytidine is a potent inhibitor of DNA methyltransferase 3a and induces apoptosis in HCT-116 colon cancer cells via Gadd45- and p53-dependent mechanisms. 2005 Feb 4
35 16007224 Genetic and epigenetic alterations of RB2/p130 tumor suppressor gene in human sporadic retinoblastoma: implications for pathogenesis and therapeutic approach. 2005 Sep 1 1
36 8790940 Selective expression of mutated p53 in human cells immortalized with either 4-nitroquinoline 1-oxide or 60Co gamma rays. 1996 Apr 2