Lysine

tumor protein p53 ; Homo sapiens







249 Article(s)
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51 26851285 Acetylation of p53 Protein at Lysine 120 Up-regulates Apaf-1 Protein and Sensitizes the Mitochondrial Apoptotic Pathway. 2016 Apr 1 4
52 26986569 Finding Potent Sirt Inhibitor in Coffee: Isolation, Confirmation and Synthesis of Javamide-II (N-Caffeoyltryptophan) as Sirt1/2 Inhibitor. 2016 1
53 27210019 Lysines in the tetramerization domain of p53 selectively modulate G1 arrest. 2016 Jun 2 5
54 27226597 Insights into Lysine Deacetylation of Natively Folded Substrate Proteins by Sirtuins. 2016 Jul 8 1
55 27535933 Lysine methylation represses p53 activity in teratocarcinoma cancer cells. 2016 Aug 30 4
56 27688818 The emerging role of lysine methyltransferase SETD8 in human diseases. 2016 1
57 27695348 A negative regulation loop of long noncoding RNA HOTAIR and p53 in non-small-cell lung cancer. 2016 1
58 27735058 Variation of free-energy landscape of the p53 C-terminal domain induced by acetylation: Enhanced conformational sampling. 2016 Dec 5 1
59 25815376 Endosome traffic machinery meets the p53-p21 axis. 2015 1
60 25825497 LLY-507, a Cell-active, Potent, and Selective Inhibitor of Protein-lysine Methyltransferase SMYD2. 2015 May 29 1
61 26021170 [Histone deacetylase inhibitors cause the TP53-dependent induction of p21/Waf1 in tumor cells carrying mutations in TP53]. 2015 1
62 26030124 The Lys-Specific Molecular Tweezer, CLR01, Modulates Aggregation of the Mutant p53 DNA Binding Domain and Inhibits Its Toxicity. 2015 Jun 23 2
63 26183023 Transcriptional activation of APAF1 by KAISO (ZBTB33) and p53 is attenuated by RelA/p65. 2015 Sep 1
64 26227335 Emerging roles of lysine methylation on non-histone proteins. 2015 Nov 1
65 26505788 Enzyme kinetics and inhibition of histone acetyltransferase KAT8. 2015 Nov 13 1
66 24038750 Oct4 maintains the pluripotency of human embryonic stem cells by inactivating p53 through Sirt1-mediated deacetylation. 2014 Jan 3
67 24151879 The discovery of novel histone lysine methyltransferase G9a inhibitors (part 1): molecular design based on a series of substituted 2,4-diamino-7- aminoalkoxyquinazoline by molecular-docking-guided 3D quantitative structure-activity relationship studies. 2014 Jun 2
68 24375404 The nucleolar protein Myb-binding protein 1A (MYBBP1A) enhances p53 tetramerization and acetylation in response to nucleolar disruption. 2014 Feb 21 1
69 24403071 Monoubiquitination is critical for ovarian tumor domain-containing ubiquitin aldehyde binding protein 1 (Otub1) to suppress UbcH5 enzyme and stabilize p53 protein. 2014 Feb 21 2
70 24528089 Histone modifications contribute to cellular replicative and hydrogen peroxide-induced premature senescence in human embryonic lung fibroblasts. 2014 May 2
71 24621507 Nuclear interactor of ARF and Mdm2 regulates multiple pathways to activate p53. 2014 1
72 24633296 Induction of tumor-reactive T helper responses by a posttranslational modified epitope from tumor protein p53. 2014 May 1
73 24667498 JMJD6 promotes colon carcinogenesis through negative regulation of p53 by hydroxylation. 2014 Mar 2
74 24691905 Functional analysis of the acetylation of human p53 in DNA damage responses. 2014 Jul 1
75 24761888 Impact of AhR, CYP1A1 and GSTM1 genetic polymorphisms on TP53 R273G mutations in individuals exposed to polycyclic aromatic hydrocarbons. 2014 1
76 24845634 Fullerenol protects retinal pigment epithelial cells from oxidative stress-induced premature senescence via activating SIRT1. 2014 May 20 1
77 24899917 Dynamics of posttranslational modifications of p53. 2014 1
78 25014164 Lysine methyltransferase Smyd2 suppresses p53-dependent cardiomyocyte apoptosis. 2014 Nov 2
79 25156493 ArhGAP30 promotes p53 acetylation and function in colorectal cancer. 2014 Aug 26 2
80 25288756 Loss of p53 induces cell proliferation via Ras-independent activation of the Raf/Mek/Erk signaling pathway. 2014 Oct 21 4
81 25521755 Ginsenoside Rg3 inhibits melanoma cell proliferation through down-regulation of histone deacetylase 3 (HDAC3) and increase of p53 acetylation. 2014 1
82 22815158 Involvement of p53 in the cytotoxic activity of the NAMPT inhibitor FK866 in myeloid leukemic cells. 2013 Feb 15 2
83 23148227 Runt-related transcription factor 1 (RUNX1) stimulates tumor suppressor p53 protein in response to DNA damage through complex formation and acetylation. 2013 Jan 11 1
84 23416275 Modulation of p53 C-terminal acetylation by mdm2, p14ARF, and cytoplasmic SirT2. 2013 Apr 2
85 23576563 ING5 is a Tip60 cofactor that acetylates p53 in response to DNA damage. 2013 Jun 15 1
86 23583237 Nucleolar protein, Myb-binding protein 1A, specifically binds to nonacetylated p53 and efficiently promotes transcriptional activation. 2013 May 10 1
87 23775793 Diverse stresses dramatically alter genome-wide p53 binding and transactivation landscape in human cancer cells. 2013 Aug 1
88 24032713 Histone trimethylation of the p53 gene by expression of a constitutively active prolactin receptor in prostate cancer cells. 2013 Oct 31 1
89 24088713 SET7/9-dependent methylation of ARTD1 at K508 stimulates poly-ADP-ribose formation after oxidative stress. 2013 Oct 2 1
90 24096875 p53's choice of myocardial death or survival: Oxygen protects infarct myocardium by recruiting p53 on NOS3 promoter through regulation of p53-Lys(118) acetylation. 2013 Nov 5
91 24194938 Acetylation of lysine 382 and phosphorylation of serine 392 in p53 modulate the interaction between p53 and MDC1 in vitro. 2013 2
92 24298606 Lysine-specific modifications of p53: a matter of life and death? 2013 Oct 3
93 24330748 Id4 dependent acetylation restores mutant-p53 transcriptional activity. 2013 Dec 13 1
94 20978925 Novel histone deacetylase inhibitor CG200745 induces clonogenic cell death by modulating acetylation of p53 in cancer cells. 2012 Apr 1
95 21963854 The HPV E6 oncoprotein targets histone methyltransferases for modulating specific gene transcription. 2012 May 3 2
96 22112863 The HDAC inhibitor depsipeptide transactivates the p53/p21 pathway by inducing DNA damage. 2012 Feb 1 2
97 22194015 Targeting protein lysine methylation and demethylation in cancers. 2012 Jan 1
98 22214662 The RAX/PACT-PKR stress response pathway promotes p53 sumoylation and activation, leading to G₁ arrest. 2012 Jan 15 1
99 22237799 Mechanisms of p53 activation and physiological relevance in the developing kidney. 2012 Apr 15 1
100 22285752 The WTX tumor suppressor enhances p53 acetylation by CBP/p300. 2012 Mar 9 1