Chloroquine

insulin ; Homo sapiens







59 Article(s)
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Title
Pub. Year
#Total Relationships
1 34104100 Repurposing New Use for Old Drug Chloroquine against Metabolic Syndrome: A Review on Animal and Human Evidence. 2021 1
2 30595379 Insulin in high concentration recede cigarette smoke extract induced cellular senescence of airway epithelial cell through autophagy pathway. 2019 Feb 5 1
3 31384309 Low dose chloroquine decreases insulin resistance in human metabolic syndrome but does not reduce carotid intima-media thickness. 2019 3
4 29976399 Resveratrol protects muscle cells against palmitate-induced cellular senescence and insulin resistance through ameliorating autophagic flux. 2018 Jul 1
5 23702482 Chloroquine stimulates glucose uptake and glycogen synthase in muscle cells through activation of Akt. 2013 Jun 14 6
6 20208057 p53 is required for chloroquine-induced atheroprotection but not insulin sensitization. 2010 Jul 1
7 19318401 Systemic lupus erythematosus presenting as hypoglycaemia with insulin receptor antibodies and insulin autoantibodies. 2009 Apr 1
8 17604495 Chloroquine-induced nitric oxide as a potential treatment of erectile dysfunction associated with the metabolic syndrome: the science and the fiction. 2007 May 1
9 16216434 Chloroquine-induced nitric oxide improves insulin sensitivity in rheumatoid arthritis. 2006 1
10 16256240 Nitric oxide might be involved in the chloroquine-improved insulin sensitivity: old treatment for global danger. 2006 Apr 1
11 17084707 Banking on ATM as a new target in metabolic syndrome. 2006 Nov 1
12 11834730 Insulin promotes the cell surface recruitment of the SAT2/ATA2 system A amino acid transporter from an endosomal compartment in skeletal muscle cells. 2002 Apr 19 1
13 12390813 [Relationship between insulin-degrading enzyme activity and insulin sensitivity in cell model of insulin-resistance]. 2002 Feb 2
14 11445552 Sulfatide promotes the folding of proinsulin, preserves insulin crystals, and mediates its monomerization. 2001 Jun 1
15 9332452 Two pathways for insulin metabolism in adipocytes. 1997 Sep 11 4
16 7487933 Chloroquine augments the binding of insulin to its receptor. 1995 Nov 1 7
17 7657617 Intracellular transport of proinsulin in pancreatic beta-cells. Structural maturation probed by disulfide accessibility. 1995 Sep 1 1
18 8338148 Five-compartment model of insulin kinetics and its use to investigate action of chloroquine in NIDDM. 1993 Jul 2
19 8487662 Effects of chloroquine on the dyslipidemia of non-insulin-dependent diabetes mellitus. 1993 Apr 1
20 1343942 Chloroquine inhibits the insulin binding and the imprinting of nuclear envelope in Tetrahymena. 1992 3
21 1874723 Proteolytic processing of the insulin receptor beta subunit is associated with insulin-induced receptor down-regulation. 1991 Aug 25 2
22 2058666 Mode of action of chloroquine in patients with non-insulin-dependent diabetes mellitus. 1991 Jun 1
23 2269328 Processing without proteolytic cleavage is required for recognition of insulin by T cells. 1990 Dec 1
24 2653825 Hepatic processing of insulin. Characterization of differential inhibition by weak bases. 1989 May 1 1
25 2692404 The characterization, regulation, and function of insulin receptors on osteoblast-like clonal osteosarcoma cell line. 1989 Dec 1
26 2460529 Antigen processing and the human T cell receptor repertoire for insulin. 1988 Nov 15 1
27 2838354 Evidence for two independent pathways of insulin-receptor internalization in hepatocytes and hepatoma cells. 1988 Jun 3
28 3283119 Intracellular insulin-receptor dissociation and segregation in a rat fibroblast cell line transfected with a human insulin receptor gene. 1988 May 5 3
29 3284910 Endocytotic uptake, processing, and retroendocytosis of human biosynthetic proinsulin by rat fibroblasts transfected with the human insulin receptor gene. 1988 May 4
30 3291555 Effect of inhibition of endocytosis, recycling and lysosomal activity on the insulin binding capacity and imprintability of Tetrahymena. 1988 2
31 3103729 Effect of chloroquine on insulin and glucose homoeostasis in normal subjects and patients with non-insulin-dependent diabetes mellitus. 1987 Feb 21 1
32 3311030 Biosynthesis of betagranin in pancreatic beta-cells. Identification of a chromogranin A-like precursor and its parallel processing with proinsulin. 1987 Jun 1 1
33 3510222 Insulin internalization and degradation in adipocytes from normal and type II diabetic subjects. 1986 Feb 5
34 3510921 Functional characteristics of decreased insulin receptors on fibroblasts obtained from a subject with severe insulin resistance and acanthosis nigricans. 1986 Feb 2
35 3513607 Insulin processing by cultured hepatocytes. 1986 Feb 9
36 3534451 Heterogeneous effects of inhibitors of receptor processing on insulin binding and intracellular accumulation in various cell types. 1986 Nov 2
37 3539101 Potentiation of specific association of insulin with HepG2 cells by phorbol esters. 1986 May 15 1
38 3541897 Insulin binding to cultured adult hepatocytes. Effects of bacitracin and chloroquine on the nature of cell-associated radioactivity. 1986 Jul 1 1
39 2581580 Hormonal and drug effects on the degradation of human myelin basic protein peptide 43-88 by alkaline proteolytic activity in the rat kidney. 1985 Apr 15 1
40 3880772 Regulation of lipoprotein lipase in primary cultures of isolated human adipocytes. 1985 Jan 1
41 3884607 Kinetics of insulin receptor internalization and recycling in adipocytes. Shunting of receptors to a degradative pathway by inhibitors of recycling. 1985 Apr 10 2
42 3885945 The effect of inhibitors of insulin processing on generation of insulin intermediate products from human fibroblast as detected by high performance liquid chromatography (HPLC). 1985 Apr 16 1
43 3902819 Degradative processing of internalized insulin in isolated adipocytes. 1985 Nov 5 1
44 3902825 The effects of cycloheximide and chloroquine on insulin receptor metabolism. Differential effects on receptor recycling and inactivation and insulin degradation. 1985 Nov 15 4
45 3915261 Inhibition of down regulation by chloroquine in cultured lymphocytes (RPMI-1788 line). 1985 Oct 3
46 3932341 Dual pathways for the intracellular processing of insulin. Relationship between retroendocytosis of intact hormone and the recycling of insulin receptors. 1985 Nov 5 4
47 6094290 In vivo chloroquine-induced inhibition of insulin degradation in a diabetic patient with severe insulin resistance. 1984 Dec 5
48 6331162 Diabetogenic effect of pentamidine. In vitro and in vivo studies in a patient with malignant insulinoma. 1984 Jul 2
49 6363165 In vitro characterization of biosynthetic human proinsulin. 1984 Feb 2
50 6389296 Insulin processing and dissociation--effect of temperature and lysosomotropic agents. 1984 Jun 1