Title : [Relationship between insulin-degrading enzyme activity and insulin sensitivity in cell model of insulin-resistance].

Pub. Date : 2002 Feb

PMID : 12390813






2 Functional Relationships(s)
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1 CONCLUSIONS: Increased IDE activity may be one of the mechanisms of IR genesis in rat primary hepatocytes cultured with high concentration of IDE, chloroquine, on the other hand, may ameliorate insulin sensitivity by inhibiting accelerated insulin degradation. Chloroquine insulin Homo sapiens
2 CONCLUSIONS: Increased IDE activity may be one of the mechanisms of IR genesis in rat primary hepatocytes cultured with high concentration of IDE, chloroquine, on the other hand, may ameliorate insulin sensitivity by inhibiting accelerated insulin degradation. Chloroquine insulin Homo sapiens