Serine

insulin ; Homo sapiens







504 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
51 26846849 Serine 302 Phosphorylation of Mouse Insulin Receptor Substrate 1 (IRS1) Is Dispensable for Normal Insulin Signaling and Feedback Regulation by Hepatic S6 Kinase. 2016 Apr 15 2
52 26929406 Loss of Interdependent Binding by the FoxO1 and FoxA1/A2 Forkhead Transcription Factors Culminates in Perturbation of Active Chromatin Marks and Binding of Transcriptional Regulators at Insulin-sensitive Genes. 2016 Apr 15 1
53 27094035 Insulin-induced cytokine production in macrophages causes insulin resistance in hepatocytes. 2016 Jun 1 2
54 27207326 Aβ-Induced Insulin Resistance and the Effects of Insulin on the Cholesterol Synthesis Pathway and Aβ Secretion in Neural Cells. 2016 Jun 1
55 27207509 Insulin-Dependent Regulation of mTORC2-Akt-FoxO Suppresses TLR4 Signaling in Human Leukocytes: Relevance to Type 2 Diabetes. 2016 Aug 1
56 27221120 Age-related impairments in skeletal muscle PDH phosphorylation and plasma lactate are indicative of metabolic inflexibility and the effects of exercise training. 2016 Jul 1 1
57 27273097 TNF-insulin crosstalk at the transcription factor GATA6 is revealed by a model that links signaling and transcriptomic data tensors. 2016 Jun 7 1
58 27387397 Protective effects of marein on high glucose-induced glucose metabolic disorder in HepG2 cells. 2016 Aug 15 1
59 27422524 Effect of the long-acting insulin analogues glargine and degludec on cardiomyocyte cell signalling and function. 2016 Jul 15 1
60 27461373 Molecular characterization of insulin resistance and glycolytic metabolism in the rat uterus. 2016 Jul 27 1
61 27470585 RKIP phosphorylation-dependent ERK1 activation stimulates adipogenic lipid accumulation in 3T3-L1 preadipocytes overexpressing LC3. 2016 Sep 9 1
62 27544192 Fucosterol activates the insulin signaling pathway in insulin resistant HepG2 cells via inhibiting PTP1B. 2016 Oct 2
63 27796268 Hyperinsulinemia augments endothelin-1 protein expression and impairs vasodilation of human skeletal muscle arterioles. 2016 Aug 1
64 25342129 Dysfunctionally phosphorylated type 1 insulin receptor substrate in neural-derived blood exosomes of preclinical Alzheimer's disease. 2015 Feb 1
65 25623542 Cell lysis-free quantum dot multicolor cellular imaging-based mechanism study for TNF-α-induced insulin resistance. 2015 Jan 27 1
66 25627174 Analysis of insulin receptor substrate signaling dynamics on microstructured surfaces. 2015 Mar 1
67 25645159 Inhibition of IRS-1 by hepatitis C virus infection leads to insulin resistance in a PTEN-dependent manner. 2015 Feb 3 1
68 25667991 Amyloid β oligomer-induced ERK1/2-dependent serine 636/639 phosphorylation of insulin receptor substrate-1 impairs insulin signaling and glycogen storage in human astrocytes. 2015 Apr 25 2
69 25701261 Insulin priming effect on estradiol-induced breast cancer metabolism and growth. 2015 1
70 25760103 Arg972 insulin receptor substrate-1 enhances tumor necrosis factor-α-induced apoptosis in osteoblasts. 2015 Jul 1
71 25854427 Insulin induces phosphorylation of serine residues of translationally controlled tumor protein in 293T cells. 2015 Apr 3 7
72 26055712 Phosphorylation-dependent Regulation of Connecdenn/DENND1 Guanine Nucleotide Exchange Factors. 2015 Jul 17 2
73 26321373 Insulin treatment promotes tyrosine phosphorylation of PKR and inhibits polyIC induced PKR threonine phosphorylation. 2015 Nov 1 2
74 26404168 NOD2 activation induces oxidative stress contributing to mitochondrial dysfunction and insulin resistance in skeletal muscle cells. 2015 Dec 1
75 26604643 Hepatitis C virus NS5A promotes insulin resistance through IRS-1 serine phosphorylation and increased gluconeogenesis. 2015 Nov 21 5
76 23832510 Hepatic cannabinoid-1 receptors mediate diet-induced insulin resistance by increasing de novo synthesis of long-chain ceramides. 2014 Jan 1
77 24068609 Chronic insulin exposure does not cause insulin resistance but is associated with chemo-resistance in colon cancer cells. 2014 Feb 2
78 24240483 Hepatitis C virus nonstructural protein 5A favors upregulation of gluconeogenic and lipogenic gene expression leading towards insulin resistance: a metabolic syndrome. 2014 May 1
79 24302004 Suppression of the mTORC1/STAT3/Notch1 pathway by activated AMPK prevents hepatic insulin resistance induced by excess amino acids. 2014 Jan 15 1
80 24535599 Phosphorylation of Grb14 BPS domain by GSK-3 correlates with complex forming of Grb14 and insulin receptor. 2014 Jun 1
81 24640977 Brain insulin resistance in Alzheimer's disease and its potential treatment with GLP-1 analogs. 2014 1
82 24642411 Structural basis of GSK-3 inhibition by N-terminal phosphorylation and by the Wnt receptor LRP6. 2014 Mar 18 1
83 24652289 Insulin and metabolic stress stimulate multisite serine/threonine phosphorylation of insulin receptor substrate 1 and inhibit tyrosine phosphorylation. 2014 May 2 12
84 24705589 Synip phosphorylation is required for insulin-stimulated Glut4 translocation and glucose uptake in podocyte. 2014 2
85 24720596 The impact of substance P on the pathogenesis of insulin resistance leading to gestational diabetes. 2014 3
86 24846082 Melatonin rescues 3T3-L1 adipocytes from FFA-induced insulin resistance by inhibiting phosphorylation of IRS-1 on Ser307. 2014 Aug 1
87 24876356 Sustained AS160 and TBC1D1 phosphorylations in human skeletal muscle 30 min after a single bout of exercise. 2014 Aug 1 2
88 24879834 The adaptor protein APPL2 inhibits insulin-stimulated glucose uptake by interacting with TBC1D1 in skeletal muscle. 2014 Nov 2
89 24939063 Gut microbiota, probiotics and diabetes. 2014 Jun 17 2
90 24979806 Role of diacylglycerol activation of PKCθ in lipid-induced muscle insulin resistance in humans. 2014 Jul 1 1
91 25002580 Deciphering a molecular mechanism of neonatal diabetes mellitus by the chemical synthesis of a protein diastereomer, [D-AlaB8]human proinsulin. 2014 Aug 22 4
92 25123125 Metabolism and insulin signaling in common metabolic disorders and inherited insulin resistance. 2014 Jul 2
93 25185805 Glucocorticoids attenuate the central sympathoexcitatory actions of insulin. 2014 Nov 15 2
94 25224502 Calcium signaling in insulin action on striated muscle. 2014 Nov 2
95 25230927 Insulin induces phosphorylation of the AMPA receptor subunit GluR1, reversed by ZIP, and over-expression of Protein Kinase M zeta, reversed by amyloid beta. 2014 Dec 1
96 25259572 Insulin resistance induced by hyperinsulinemia coincides with a persistent alteration at the insulin receptor tyrosine kinase domain. 2014 1
97 25365322 Fibroblast growth factor 21 improves insulin sensitivity and synergizes with insulin in human adipose stem cell-derived (hASC) adipocytes. 2014 1
98 25525174 Pioglitazone restores IGFBP-3 levels through DNA PK in retinal endothelial cells cultured in hyperglycemic conditions. 2014 Dec 18 1
99 25580119 Alternate Phosphorylation/O-GlcNAc Modification on Human Insulin IRSs: A Road towards Impaired Insulin Signaling in Alzheimer and Diabetes. 2014 4
100 23204326 Cardiac PI3K-Akt impairs insulin-stimulated glucose uptake independent of mTORC1 and GLUT4 translocation. 2013 Jan 2