Guanosine Triphosphate

insulin ; Homo sapiens







75 Article(s)
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Title
Pub. Year
#Total Relationships
1 32867592 Roles of GTP and Rho GTPases in pancreatic islet beta cell function and dysfunction. 2021 Sep-Nov 2
2 34551282 KARATE: PKA-induced KRAS4B-RHOA-mTORC2 supercomplex phosphorylates AKT in insulin signaling and glucose homeostasis. 2021 Nov 18 1
3 30647914 Cryo-EM insight into the structure of MTOR complex 1 and its interactions with Rheb and substrates. 2019 1
4 30407917 Kalirin/Trio Rho GDP/GTP exchange factors regulate proinsulin and insulin secretion. 2018 Nov 1 1
5 28202288 Tiam1/Vav2-Rac1 axis: A tug-of-war between islet function and dysfunction. 2017 May 15 1
6 27226625 Elmo2 Is a Regulator of Insulin-dependent Glut4 Membrane Translocation. 2016 Jul 29 1
7 27321586 Glucose and GTP-binding protein-coupled receptor cooperatively regulate transient receptor potential-channels to stimulate insulin secretion [Review]. 2016 Oct 29 1
8 25897360 Interplay between Rab27a effectors in pancreatic β-cells. 2015 Apr 15 2
9 25947911 GTP- and GDP-Dependent Rab27a Effectors in Pancreatic Beta-Cells. 2015 2
10 28509184 Mizoribine-induced severe hyperglycemia in a patient with microscopic polyangiitis. 2014 Nov 2
11 23804653 Specialized sorting of GLUT4 and its recruitment to the cell surface are independently regulated by distinct Rabs. 2013 Aug 1
12 21070828 The structure and allosteric regulation of glutamate dehydrogenase. 2011 Sep 1
13 21187662 Rab27a, actin and beta-cell endocytosis. 2011 2
14 21454697 Insulin-stimulated GLUT4 protein translocation in adipocytes requires the Rab10 guanine nucleotide exchange factor Dennd4C. 2011 May 13 1
15 18765678 Amino acid regulation of TOR complex 1. 2009 Apr 1
16 19143636 Activation of mTORC1 in two steps: Rheb-GTP activation of catalytic function and increased binding of substrates to raptor. 2009 Feb 1
17 19531491 Novel inhibitors complexed with glutamate dehydrogenase: allosteric regulation by control of protein dynamics. 2009 Aug 21 1
18 18076383 Rab10 in insulin-stimulated GLUT4 translocation. 2008 Apr 1 1
19 18676370 Re-evaluating the roles of proposed modulators of mammalian target of rapamycin complex 1 (mTORC1) signaling. 2008 Nov 7 1
20 18948252 CDK5-dependent phosphorylation of the Rho family GTPase TC10(alpha) regulates insulin-stimulated GLUT4 translocation. 2008 Dec 19 1
21 17141178 The discovery of signal transduction by G proteins: a personal account and an overview of the initial findings and contributions that led to our present understanding. 2007 Apr 1
22 17158030 A novel method to monitor insulin-stimulated GTP-loading of Rab11a in cardiomyocytes. 2007 Apr 2
23 17956307 Amino acid metabolism, insulin secretion and diabetes. 2007 Nov 1
24 18003705 Rip11 is a Rab11- and AS160-RabGAP-binding protein required for insulin-stimulated glucose uptake in adipocytes. 2007 Dec 1 1
25 16545078 Regulation of small GTP-binding proteins by insulin. 2006 Apr 3
26 16957985 Regulatory roles for nm23/nucleoside diphosphate kinase-like enzymes in insulin secretion from the pancreatic islet beta cell. 2006 Aug 1
27 15486046 Mechanism of SHIP-mediated inhibition of insulin- and platelet-derived growth factor-stimulated mitogen-activated protein kinase activity in 3T3-L1 adipocytes. 2005 Feb 2
28 15739119 A role for heterotrimeric GTP-binding proteins and ERK1/2 in insulin-mediated, nitric-oxide-dependent, cyclic GMP production in human umbilical vein endothelial cells. 2005 Mar 2
29 12970678 p53-independent induction of p21(waf1/cip1) contributes to the activation of caspases in GTP-depletion-induced apoptosis of insulin-secreting cells. 2004 Jan 2
30 11903050 Expression, purification and characterization of human glutamate dehydrogenase (GDH) allosteric regulatory mutations. 2002 Apr 1 1
31 11336646 Expression of a prenylation-deficient Rab4 inhibits the GLUT4 translocation induced by active phosphatidylinositol 3-kinase and protein kinase B. 2001 May 15 1
32 10702285 The trimeric GTP-binding protein (G(q)/G(11)) alpha subunit is required for insulin-stimulated GLUT4 translocation in 3T3L1 adipocytes. 2000 Mar 10 3
33 10971790 Gamma-glutamyl transpeptidase and the metabolic syndrome. 2000 Sep 3
34 9914469 Molecular mechanisms and regulation of insulin exocytosis as a paradigm of endocrine secretion. 1999 Jan 1
35 9585135 Activation of PI 3-kinase by G protein betagamma subunits. 1998 2
36 9609111 Insulin regulation of the Ras activation/inactivation cycle. 1998 May 1
37 9751484 Insulin potentiates platelet-derived growth factor action in vascular smooth muscle cells. 1998 Oct 1
38 10212832 Role of SNARE's in the GLUT4 translocation response to insulin in adipose cells and muscle. 1998 1
39 9345266 GTP loading of farnesylated p21Ras by insulin at the plasma membrane. 1997 Oct 9 3
40 9388696 In situ labelling of insulin stimulated GTP-binding proteins in adipocytes. 1997 Aug 1
41 8663461 Insulin and epidermal growth factor receptors regulate distinct pools of Grb2-SOS in the control of Ras activation. 1996 Jul 26 1
42 8713074 Synergistic activation of PtdIns 3-kinase by tyrosine-phosphorylated peptide and beta gamma-subunits of GTP-binding proteins. 1996 Jul 15 1
43 8951345 On the tyrosine kinase mechanism of the novel effect of insulin and insulinlike growth factor I. Stimulation of the adenylyl cyclase system in muscle tissues. 1996 Dec 24 1
44 7535775 Insulin-dependent tyrosine phosphorylation of the vav protooncogene product in cells of hematopoietic origin. 1995 Mar 31 2
45 7540866 Signal transduction pathways leading to insulin-induced early gene induction. 1995 Jun 27 1
46 7592690 Negative feedback regulation and desensitization of insulin- and epidermal growth factor-stimulated p21ras activation. 1995 Oct 27 1
47 8590382 Involvement of the adenylyl cyclase signaling system in the action of insulin and mollusk insulin-like peptide. 1995 Dec 2
48 21153201 Mechanism of activation of guanine nucleotide exchange factor by insulin. 1995 Jul 2
49 7848909 Insulin and insulin-like growth factor signaling are defective in the MDA MB-468 human breast cancer cell line. 1994 Oct 1
50 7918472 Characterization of nucleoside diphosphokinase activity in human and rodent pancreatic beta cells: evidence for its role in the formation of guanosine triphosphate, a permissive factor for nutrient-induced insulin secretion. 1994 Oct 18 1