Title : Activation of PI 3-kinase by G protein betagamma subunits.

Pub. Date : 1998

PMID : 9585135






2 Functional Relationships(s)
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1 We have reported that fMLP-induced activation of pertussis toxin-sensitive GTP-binding proteins in THP-1 cells potentiates the insulin-induced accumulation of PtdIns(3,4,5)P3, a product of phosphoinositide 3-kinase (T. Okada et al., Biochem. Guanosine Triphosphate insulin Homo sapiens
2 In rat adipocytes, which represent the physiological target cells of insulin, receptor-mediated activation of GTP-binding protein by adenosine and prostaglandin E2 potentiated the insulin-induced PtdIns(3,4,5)P3 accumulation. Guanosine Triphosphate insulin Homo sapiens