Acetylglucosamine

O-linked N-acetylglucosamine (GlcNAc) transferase ; Homo sapiens







142 Article(s)
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1 34981577 O-GlcNAcylation regulates β1,4-GlcNAc-branched N-glycan biosynthesis via the OGT/SLC35A3/GnT-IV axis. 2022 Feb 1
2 35296731 Increased O-GlcNAcylation promotes IGF-1 receptor/PhosphatidyI Inositol-3 kinase/Akt pathway in cervical cancer cells. 2022 Mar 16 2
3 35356257 Ogt Demonstrated Conspicuous Clinical Significance in Cancers, from Pan-Cancer to Small-Cell Lung Cancer. 2022 2
4 35625898 Targeted Inhibition of O-Linked β-N-Acetylglucosamine Transferase as a Promising Therapeutic Strategy to Restore Chemosensitivity and Attenuate Aggressive Tumor Traits in Chemoresistant Urothelial Carcinoma of the Bladder. 2022 May 18 1
5 32929277 MYPT1 O-GlcNAc modification regulates sphingosine-1-phosphate mediated contraction. 2021 Feb 1
6 33333092 Elucidating the protein substrate recognition of O-GlcNAc transferase (OGT) toward O-GlcNAcase (OGA) using a GlcNAc electrophilic probe. 2021 Feb 1 4
7 33472950 O-GlcNAc Transferase - An Auxiliary Factor or a Full-blown Oncogene? 2021 Apr 4
8 33789105 Ogt controls neural stem/progenitor cell pool and adult neurogenesis through modulating Notch signaling. 2021 Mar 30 1
9 33801653 Feedback Regulation of O-GlcNAc Transferase through Translation Control to Maintain Intracellular O-GlcNAc Homeostasis. 2021 Mar 27 2
10 33950562 O-GlcNAc Engineering on a Target Protein in Cells with Nanobody-OGT and Nanobody-splitOGA. 2021 May 1
11 34135600 O-GlcNAcylation Prediction: An Unattained Objective. 2021 4
12 34186233 Nanomolar inhibition of human OGA by 2-acetamido-2-deoxy-d-glucono-1,5-lactone semicarbazone derivatives. 2021 Nov 5 2
13 34348917 RUNX1 can mediate the glucose and O-GlcNAc-driven proliferation and migration of human retinal microvascular endothelial cells. 2021 Aug 1
14 34391182 OGT regulated O-GlcNacylation promotes migration and invasion by activating IL-6/STAT3 signaling in NSCLC cells. 2021 Sep 1
15 34502531 OGT Protein Interaction Network (OGT-PIN): A Curated Database of Experimentally Identified Interaction Proteins of OGT. 2021 Sep 6 2
16 34646892 Inhibiting Hyper-O-GlcNAcylation of c-Myc accelerate diabetic wound healing by alleviating keratinocyte dysfunction. 2021 1
17 34725712 Truncation of the TPR domain of OGT alters substrate and glycosite selection. 2021 Dec 2
18 34726899 Multidimensional Free Energy and Accelerated Quantum Library Methods Provide a Gateway to Glycoenzyme Conformational, Electronic, and Reaction Mechanisms. 2021 Nov 16 3
19 34783346 Writing and erasing O-GlcNAc from target proteins in cells. 2021 Dec 17 1
20 34837015 O-GlcNAcylation in health and neurodegenerative diseases. 2021 Nov 1
21 34868034 O-GlcNAcylation in Chronic Lymphocytic Leukemia and Other Blood Cancers. 2021 1
22 34948036 TET3- and OGT-Dependent Expression of Genes Involved in Epithelial-Mesenchymal Transition in Endometrial Cancer. 2021 Dec 8 2
23 34950703 The Identification of a Novel Calcium-Dependent Link Between NAD+ and Glucose Deprivation-Induced Increases in Protein O-GlcNAcylation and ER Stress. 2021 1
24 31630803 Evidence of a compensatory regulation of colonic O-GlcNAc transferase and O-GlcNAcase expression in response to disruption of O-GlcNAc homeostasis. 2020 Jan 1 2
25 31924761 O-GlcNAc transferase inhibits visceral fat lipolysis and promotes diet-induced obesity. 2020 Jan 10 1
26 32014551 Regulation of cardiac O-GlcNAcylation: More than just nutrient availability. 2020 May 1 1
27 32080367 An intellectual disability syndrome with single-nucleotide variants in O-GlcNAc transferase. 2020 Jun 3
28 32114385 Enhanced O-linked Glcnacylation in Crohn's disease promotes intestinal inflammation. 2020 Mar 1
29 32201074 Contribution of extracellular O-GlcNAc to the stability of folded epidermal growth factor-like domains and Notch1 trafficking. 2020 May 21 1
30 32406185 O-GlcNAc Transferase: Structural Characteristics, Catalytic Mechanism and Small-Molecule Inhibitors. 2020 Nov 2 1
31 32863226 Specific O-GlcNAc modification at Ser-615 modulates eNOS function. 2020 Sep 1
32 32994395 Mutual regulation between OGT and XIAP to control colon cancer cell growth and invasion. 2020 Sep 29 1
33 33192538 OGT-Mediated KEAP1 Glycosylation Accelerates NRF2 Degradation Leading to High Phosphate-Induced Vascular Calcification in Chronic Kidney Disease. 2020 2
34 33194731 Functional Analysis of O-GlcNAcylation in Cancer Metastasis. 2020 4
35 33199824 O-GlcNAc stabilizes SMAD4 by inhibiting GSK-3β-mediated proteasomal degradation. 2020 Nov 16 1
36 30199580 Chemical and Biochemical Strategies To Explore the Substrate Recognition of O-GlcNAc-Cycling Enzymes. 2019 Feb 1 1
37 30412792 Diminished O-GlcNAcylation in Alzheimer's disease is strongly correlated with mitochondrial anomalies. 2019 Aug 1 1
38 30550897 Uridine diphosphate release mechanism in O-N-acetylglucosamine (O-GlcNAc) transferase catalysis. 2019 Mar 3
39 30865517 Acute increases in O-GlcNAc indirectly impair mitochondrial bioenergetics through dysregulation of LonP1-mediated mitochondrial protein complex turnover. 2019 Jun 1 1
40 31237748 Mechanical stress alters protein O-GlcNAc in human periodontal ligament cells. 2019 Sep 1
41 28929346 O-GlcNAc-Dependent Regulation of Progesterone Receptor Function in Breast Cancer. 2018 Feb 3
42 29485866 O-GlcNAc Transferase Recognizes Protein Substrates Using an Asparagine Ladder in the Tetratricopeptide Repeat (TPR) Superhelix. 2018 Mar 14 3
43 29524020 Cross regulation between mTOR signaling and O-GlcNAcylation. 2018 Jun 3
44 29769320 O-GlcNAc transferase missense mutations linked to X-linked intellectual disability deregulate genes involved in cell fate determination and signaling. 2018 Jul 6 5
45 29771506 The Metabolic Chemical Reporter 6-Azido-6-deoxy-glucose Further Reveals the Substrate Promiscuity of O-GlcNAc Transferase and Catalyzes the Discovery of Intracellular Protein Modification by O-Glucose. 2018 Jun 13 1
46 30459708 Involvement of O-GlcNAcylation in the Skeletal Muscle Physiology and Physiopathology: Focus on Muscle Metabolism. 2018 2
47 30517873 ULK1 O-GlcNAcylation Is Crucial for Activating VPS34 via ATG14L during Autophagy Initiation. 2018 Dec 4 2
48 30693278 Production of Glycopeptide Derivatives for Exploring Substrate Specificity of Human OGA Toward Sugar Moiety. 2018 1
49 27345396 O-GlcNAcylation regulates breast cancer metastasis via SIRT1 modulation of FOXM1 pathway. 2017 Jan 26 1
50 27918560 Genome-wide chemical mapping of O-GlcNAcylated proteins in Drosophila melanogaster. 2017 Feb 1