Title : Targeted Inhibition of O-Linked β-N-Acetylglucosamine Transferase as a Promising Therapeutic Strategy to Restore Chemosensitivity and Attenuate Aggressive Tumor Traits in Chemoresistant Urothelial Carcinoma of the Bladder.

Pub. Date : 2022 May 18

PMID : 35625898






1 Functional Relationships(s)
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1 Elevated glucose flux through the abnormal upregulation of O-linked beta-N-acetylglucosamine (O-GlcNAc) transferase (OGT) controls key signaling and metabolic pathways regulating diverse cancer cell phenotypes. Acetylglucosamine O-linked N-acetylglucosamine (GlcNAc) transferase Homo sapiens