Uridine Diphosphate N-Acetylglucosamine

O-linked N-acetylglucosamine (GlcNAc) transferase ; Homo sapiens







71 Article(s)
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1 34800629 O-GlcNAcylation regulation of cellular signaling in cancer. 2022 Feb 1
2 35185892 Protein O-GlcNAcylation Regulates Innate Immune Cell Function. 2022 4
3 35296731 Increased O-GlcNAcylation promotes IGF-1 receptor/PhosphatidyI Inositol-3 kinase/Akt pathway in cervical cancer cells. 2022 Mar 16 1
4 35348747 VPRBP functions downstream of the androgen receptor and OGT to restrict p53 activation in prostate cancer. 2022 Mar 29 4
5 33098688 A missense mutation in a patient with developmental delay affects the activity and structure of the hexosamine biosynthetic pathway enzyme AGX1. 2021 Jan 1
6 34803603 Proteomic Profiling of Astrocytic O-GlcNAc Transferase-Related Proteins in the Medial Prefrontal Cortex. 2021 2
7 32628333 ELT-2 promotes O-GlcNAc transferase OGT-1 expression to modulate Caenorhabditis elegans lifespan. 2020 Jul 6 3
8 30550897 Uridine diphosphate release mechanism in O-N-acetylglucosamine (O-GlcNAc) transferase catalysis. 2019 Mar 1
9 30885209 NF-κB upregulates glutamine-fructose-6-phosphate transaminase 2 to promote migration in non-small cell lung cancer. 2019 Mar 18 2
10 28722313 Cellular glycosylation senses metabolic changes and modulates cell plasticity during epithelial to mesenchymal transition. 2018 Mar 1
11 29513364 UDP-GlcNAc Analogues as Inhibitors of O-GlcNAc Transferase (OGT): Spectroscopic, Computational, and Biological Studies. 2018 May 17 2
12 29594839 O-GlcNAc in cancer: An Oncometabolism-fueled vicious cycle. 2018 Jun 1
13 30082471 Hexosamine Biosynthetic Pathway Inhibition Leads to AML Cell Differentiation and Cell Death. 2018 Oct 2
14 30108977 Inhibition of O-GlcNAc transferase (OGT) by peptidic hybrids. 2018 May 1 2
15 30224358 The conserved threonine-rich region of the HCF-1PRO repeat activates promiscuous OGT:UDP-GlcNAc glycosylation and proteolysis activities. 2018 Nov 16 1
16 30237786 Real Talk: The Inter-play Between the mTOR, AMPK, and Hexosamine Biosynthetic Pathways in Cell Signaling. 2018 2
17 30356686 Cross-Dysregulation of O-GlcNAcylation and PI3K/AKT/mTOR Axis in Human Chronic Diseases. 2018 4
18 30693278 Production of Glycopeptide Derivatives for Exploring Substrate Specificity of Human OGA Toward Sugar Moiety. 2018 1
19 27935279 Catalytic Promiscuity of O-GlcNAc Transferase Enables Unexpected Metabolic Engineering of Cytoplasmic Proteins with 2-Azido-2-deoxy-glucose. 2017 Jan 20 2
20 29456783 The Role of Stress-Induced O-GlcNAc Protein Modification in the Regulation of Membrane Transport. 2017 2
21 26369908 Identification and biological consequences of the O-GlcNAc modification of the human innate immune receptor, Nod2. 2016 Jan 1
22 26883802 UDP-sugar substrates of HAS3 regulate its O-GlcNAcylation, intracellular traffic, extracellular shedding and correlate with melanoma progression. 2016 Aug 3
23 26887390 Hexosamine biosynthesis in keratinocytes: roles of GFAT and GNPDA enzymes in the maintenance of UDP-GlcNAc content and hyaluronan synthesis. 2016 Jul 2
24 27056667 Proteolysis of HCF-1 by Ser/Thr glycosylation-incompetent O-GlcNAc transferase:UDP-GlcNAc complexes. 2016 Apr 15 3
25 27114449 A Novel Quantitative Mass Spectrometry Platform for Determining Protein O-GlcNAcylation Dynamics. 2016 Jul 1
26 27252680 Silencing the Nucleocytoplasmic O-GlcNAc Transferase Reduces Proliferation, Adhesion, and Migration of Cancer and Fetal Human Colon Cell Lines. 2016 2
27 25731954 Exploring reaction pathways for O-GlcNAc transferase catalysis. A string method study. 2015 Mar 26 4
28 26240142 Enhanced transfer of a photocross-linking N-acetylglucosamine (GlcNAc) analog by an O-GlcNAc transferase mutant with converted substrate specificity. 2015 Sep 11 6
29 26305326 Distinct OGT-Binding Sites Promote HCF-1 Cleavage. 2015 1
30 26499076 O-Linked N-acetylglucosaminylation of Sp1 interferes with Sp1 activation of glycolytic genes. 2015 Dec 4-11 2
31 24524620 Functional O-GlcNAc modifications: implications in molecular regulation and pathophysiology. 2014 Mar-Apr 2
32 24630721 Spliced X-box binding protein 1 couples the unfolded protein response to hexosamine biosynthetic pathway. 2014 Mar 13 1
33 24759912 O-GlcNAc and neurodegeneration: biochemical mechanisms and potential roles in Alzheimer's disease and beyond. 2014 Oct 7 1
34 25148700 The mitochondrial O-linked N-acetylglucosamine transferase (mOGT) in the diabetic patient could be the initial trigger to develop Alzheimer disease. 2014 Oct 4
35 23592772 Hyper-O-GlcNAcylation is anti-apoptotic and maintains constitutive NF-κB activity in pancreatic cancer cells. 2013 May 24 2
36 23765660 Antibodies and activity measurements for the detection of O-GlcNAc transferase and assay of its substrate, UDP-GlcNAc. 2013 2
37 23935944 O-GlcNAcylation-inducing treatments inhibit estrogen receptor α expression and confer resistance to 4-OH-tamoxifen in human breast cancer-derived MCF-7 cells. 2013 2
38 21374590 Suppression of Glutamine:fructose-6-phosphate amidotransferase-1 inhibits adipogenesis in 3T3-L1 adipocytes. 2012 Jan 1
39 22311971 Insights into O-linked N-acetylglucosamine ([0-9]O-GlcNAc) processing and dynamics through kinetic analysis of O-GlcNAc transferase and O-GlcNAcase activity on protein substrates. 2012 May 4 1
40 20640461 Substrate and product analogues as human O-GlcNAc transferase inhibitors. 2011 Mar 3
41 21240259 Structure of human O-GlcNAc transferase and its complex with a peptide substrate. 2011 Jan 27 2
42 21273069 6''-Azido-6''-deoxy-UDP-N-acetylglucosamine as a glycosyltransferase substrate. 2011 Feb 15 1
43 21697645 Glucosamine induces cell death via proteasome inhibition in human ALVA41 prostate cancer cell. 2011 Sep 30 1
44 19647043 The hexosamine signaling pathway: O-GlcNAc cycling in feast or famine. 2010 Feb 2
45 20396401 Mechanism, Structure, and Inhibition of O-GlcNAc Processing Enzymes. 2010 Jan 2
46 20417205 Site-specific interplay between O-GlcNAcylation and phosphorylation in cellular regulation. 2010 Jun 18 1
47 20466550 O-GlcNAc signaling: a metabolic link between diabetes and cancer? 2010 Oct 1
48 17909453 Hexosamine biosynthesis and protein O-glycosylation: the first line of defense against stress, ischemia, and trauma. 2008 Apr 1
49 18039537 A convenient synthesis of the C-1-phosphonate analogue of UDP-GlcNAc and its evaluation as an inhibitor of O-linked GlcNAc transferase (OGT). 2008 Feb 4 2
50 18536723 Structure of an O-GlcNAc transferase homolog provides insight into intracellular glycosylation. 2008 Jul 2