Pub. Date : 2020 Jul 6
PMID : 32628333
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | 5O-GlcNAc transferase (OGT) is the enzyme catalyzing protein O-GlcNAcylation by addition of a single O-linked-beta-N-acetylglucosamine molecule (O-GlcNAc) to nuclear and cytoplasmic targets, and it uses uridine diphosphate-N-acetylglucosamine (UDP-GlcNAc) as a donor. | Uridine Diphosphate N-Acetylglucosamine | O-linked N-acetylglucosamine (GlcNAc) transferase | Homo sapiens |
| 2 | 5O-GlcNAc transferase (OGT) is the enzyme catalyzing protein O-GlcNAcylation by addition of a single O-linked-beta-N-acetylglucosamine molecule (O-GlcNAc) to nuclear and cytoplasmic targets, and it uses uridine diphosphate-N-acetylglucosamine (UDP-GlcNAc) as a donor. | Uridine Diphosphate N-Acetylglucosamine | O-linked N-acetylglucosamine (GlcNAc) transferase | Homo sapiens |
| 3 | As UDP-GlcNAc is the final product of the nutrient-sensing hexosamine signaling pathway, overexpression or knockout of ogt in mammals or invertebrate models influences cellular nutrient-response signals and increases susceptibility to chronic diseases of aging. | Uridine Diphosphate N-Acetylglucosamine | O-linked N-acetylglucosamine (GlcNAc) transferase | Homo sapiens |