Vitamin A

lecithin retinol acyltransferase ; Homo sapiens







58 Article(s)
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1 33052059 Vitamin A deficiency indicating as low expression of LRAT may be a novel biomarker of primary hypertension. 2021 Feb 17 2
2 34836244 Vitamin A Transporters in Visual Function: A Mini Review on Membrane Receptors for Dietary Vitamin A Uptake, Storage, and Transport to the Eye. 2021 Nov 9 2
3 32605249 Vitamin A Rich Diet Diminishes Early Urothelial Carcinogenesis by Altering Retinoic Acid Signaling. 2020 Jun 28 1
4 28758396 Impact of LCA-Associated E14L LRAT Mutation on Protein Stability and Retinoid Homeostasis. 2017 Aug 29 2
5 26880640 The coordinated action of lecithin:retinol acyltransferase and cellular retinol-binding proteins for regulation of vitamin A esterification. 2016 Mar 9
6 25317684 Transgenic reporter mice with promoter region of murine LRAT specifically marks lens and meiosis spermatocytes. 2015 1
7 25383759 LRAT-specific domain facilitates vitamin A metabolism by domain swapping in HRASLS3. 2015 Jan 2
8 25481334 Signaling by retinol and its serum binding protein. 2015 Feb 1
9 23890161 Hepatic stellate cells that coexpress LRAT and CRBP-1 partially contribute to portal fibrogenesis in patients with human viral hepatitis. 2014 Feb 1
10 25236354 Knockdown of lecithin retinol acyltransferase increases all-trans retinoic acid levels and restores retinoid sensitivity in malignant melanoma cells. 2014 Nov 6
11 25260806 High incidence of LRAT promoter hypermethylation in colorectal cancer correlates with tumor stage. 2014 Nov 3
12 23155051 The retinol dehydrogenase Rdh10 localizes to lipid droplets during acyl ester biosynthesis. 2013 Jan 4 1
13 23688744 The role of retinoic acid receptors in activated hepatic stellate cells. 2013 Aug 2
14 24433184 Lecithin retinol acyltransferase as a potential prognostic marker for malignant melanoma. 2013 Nov 1
15 21465477 Vitamin A metabolism in benign and malignant melanocytic skin cells: importance of lecithin/retinol acyltransferase and RPE65. 2012 Feb 5
16 22260449 Binding of a truncated form of lecithin:retinol acyltransferase and its N- and C-terminal peptides to lipid monolayers. 2012 Feb 21 2
17 22815070 STRA6-catalyzed vitamin A influx, efflux, and exchange. 2012 Nov 1
18 20356843 FATP1 inhibits 11-cis retinol formation via interaction with the visual cycle retinoid isomerase RPE65 and lecithin:retinol acyltransferase. 2010 Jun 11 1
19 20628054 An acyl-covalent enzyme intermediate of lecithin:retinol acyltransferase. 2010 Sep 17 1
20 18652909 Retinoic acid receptors and GATA transcription factors activate the transcription of the human lecithin:retinol acyltransferase gene. 2009 Mar 3
21 19171200 The involvement of cytochrome p450 (CYP) 26 in the retinoic acid metabolism of human epidermal keratinocytes. 2009 Mar 1
22 19294396 Both all-trans retinoic acid and cytochrome P450 (CYP26) inhibitors affect the expression of vitamin A metabolizing enzymes and retinoid biomarkers in organotypic epidermis. 2009 Aug 2
23 19665987 An essential set of basic DNA response elements is required for receptor-dependent transcription of the lecithin:retinol acyltransferase (Lrat) gene. 2009 Sep 2
24 18093970 Retinyl ester formation by lecithin: retinol acyltransferase is a key regulator of retinoid homeostasis in mouse embryogenesis. 2008 Feb 29 2
25 18284914 Secondary structure of a truncated form of lecithin retinol acyltransferase in solution and evidence for its binding and hydrolytic action in monolayers. 2008 May 2
26 18316031 RBP4 disrupts vitamin A uptake homeostasis in a STRA6-deficient animal model for Matthew-Wood syndrome. 2008 Mar 2
27 18823527 A genome-wide association study for late-onset Alzheimer's disease using DNA pooling. 2008 Sep 29 1
28 17068359 Cell proliferation inhibition and alterations in retinol esterification induced by phytanic acid and docosahexaenoic acid. 2007 Jan 2
29 17114808 Topology and membrane association of lecithin: retinol acyltransferase. 2007 Jan 19 2
30 16939223 Palmitoyl transferase activity of lecithin retinol acyl transferase. 2006 Sep 5 2
31 17016651 Reduced lecithin:retinol acyltransferase expression in human breast cancer. 2006 Nov 1
32 14704332 Regulation of hepatic retinol metabolism: perspectives from studies on vitamin A status. 2004 Jan 10
33 15147196 Roles of cysteine 161 and tyrosine 154 in the lecithin-retinol acyltransferase mechanism. 2004 May 25 2
34 15474300 Cloning, gene organization and identification of an alternative splicing process in lecithin:retinol acyltransferase cDNA from human liver. 2004 Oct 27 2
35 12741839 All-trans-retinyl esters are the substrates for isomerization in the vertebrate visual cycle. 2003 May 20 3
36 12755610 Purification and characterization of a transmembrane domain-deleted form of lecithin retinol acyltransferase. 2003 May 27 2
37 14581364 Differential expression of the enzyme that esterifies retinol, lecithin:retinol acyltransferase, in subtypes of human renal cancer and normal kidney. 2003 Oct 15 1
38 14596594 Lecithin retinol acyltransferase is a founder member of a novel family of enzymes. 2003 Nov 11 2
39 11912136 Retinol metabolism and lecithin:retinol acyltransferase levels are reduced in cultured human prostate cancer cells and tissue specimens. 2002 Mar 15 4
40 12009892 Lecithin retinol acyltransferase forms functional homodimers. 2002 May 21 4
41 12419830 Human melanomas of fibroblast and epithelial morphology differ widely in their ability to synthesize retinyl esters. 2002 Nov 1
42 11231005 Two histidine residues are essential for catalysis by lecithin retinol acyl transferase. 2001 Jan 26 2
43 11766909 Retinoic acid homeostasis: retinoic acid regulates liver retinol esterification as well as its own catabolic oxidation in liver. 2001 Dec 4
44 10819989 Lecithin retinol acyltransferase contains cysteine residues essential for catalysis. 2000 May 2 2
45 11062150 Esterification of all-trans-retinol in normal human epithelial cell strains and carcinoma lines from oral cavity, skin and breast: reduced expression of lecithin:retinol acyltransferase in carcinoma lines. 2000 Nov 1
46 9920938 Molecular and biochemical characterization of lecithin retinol acyltransferase. 1999 Feb 5 3
47 9989277 Reduced lecithin:retinol acyl transferase activity in cultured squamous cell carcinoma lines results in increased substrate-driven retinoic acid synthesis. 1999 Jan 4 2
48 10462172 Retinol esterification activity contributes to retinol transport in stellate cells. 1999 Jun 6
49 9862453 Lack of effect of RPE65 removal on the enzymatic processing of all-trans-retinol into 11-cis-retinol in vitro. 1998 Nov 27 2
50 9147140 Retinyl ester storage is altered in liver stellate cells and in HL60 cells transfected with cellular retinol-binding protein type I. 1997 Feb 2