Cisplatin

CASP8 and FADD like apoptosis regulator ; Homo sapiens







18 Article(s)
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1 31838086 Cisplatin unleashes Toll-like receptor 3-mediated apoptosis through the downregulation of c-FLIP in malignant mesothelioma. 2020 Mar 1 2
2 33302576 Inhibition of Drp1 Sensitizes Cancer Cells to Cisplatin-Induced Apoptosis through Transcriptional Inhibition of c-FLIP Expression. 2020 Dec 8 2
3 28863158 c-FLIP and the NOXA/Mcl-1 axis participate in the synergistic effect of pemetrexed plus cisplatin in human choroidal melanoma cells. 2017 3
4 25682199 Synergistic anticancer effect of cisplatin and Chal-24 combination through IAP and c-FLIPL degradation, Ripoptosome formation and autophagy-mediated apoptosis. 2015 Jan 30 2
5 26273359 Effects of histone deacetylase inhibitor trichostatin A combined with cisplatin on apoptosis of A549 cell line. 2015 Mar 1
6 23313194 The role of c-FLIP in cisplatin resistance of human bladder cancer cells. 2013 Jun 6
7 23912708 Combination of Ad-sTRAIL with the chemotherapeutic drug cisplatin synergistically enhances their pro-apoptotic ability in human breast cancer cells. 2013 Oct 1
8 20876774 Identification of c-FLIP(L) and c-FLIP(S) as critical regulators of death receptor-induced apoptosis in pancreatic cancer cells. 2011 Feb 2
9 21877938 Cisplatin restores TRAIL apoptotic pathway in glioblastoma-derived stem cells through up-regulation of DR5 and down-regulation of c-FLIP. 2011 Oct 2
10 18559494 Cisplatin induces p53-dependent FLICE-like inhibitory protein ubiquitination in ovarian cancer cells. 2008 Jun 15 1
11 18675507 Short hairpin RNA targeting c-FLIP sensitizes human cervical adenocarcinoma Hela cells to chemotherapy and radiotherapy. 2008 Nov 28 1
12 17693058 Inhibition of RIP and c-FLIP enhances TRAIL-induced apoptosis in pancreatic cancer cells. 2007 Nov 1
13 17973862 Resistance to Fas-mediated apoptosis in malignant tumours is rescued by KN-93 and cisplatin via downregulation of c-FLIP expression and phosphorylation. 2007 Dec 4
14 15644494 Cross-resistance to death ligand-induced apoptosis in cisplatin-selected HeLa cells associated with overexpression of DDB2 and subsequent induction of cFLIP. 2005 Apr 1
15 12845662 Enhanced susceptibility of oral squamous cell carcinoma cell lines to FAS-mediated apoptosis by cisplatin and 5-fluorouracil. 2003 Sep 10 1
16 12919886 Chemotherapeutic agents sensitize sarcoma cell lines to tumor necrosis factor-related apoptosis-inducing ligand-induced caspase-8 activation, apoptosis and loss of mitochondrial membrane potential. 2003 Sep 1
17 14519653 Cisplatin down-regulation of cellular Fas-associated death domain-like interleukin-1beta-converting enzyme-like inhibitory proteins to restore tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human melanoma cells. 2003 Sep 15 3
18 12642689 Role of MRIT/cFLIP in protection against chemotherapy-induced apoptosis. 2002 Nov-Dec 1