Oligonucleotides

apolipoprotein B ; Homo sapiens







67 Article(s)
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Pub. Year
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1 35221690 Mipomersen in Familial Hypercholesterolemia: An Update on Health-Related Quality of Life and Patient-Reported Outcomes. 2022 1
2 33603500 Novel Experimental Agents for the Treatment of Hypercholesterolemia. 2021 1
3 34357325 The Effect of Mipomersen in the Management of Patients with Familial Hypercholesterolemia: A Systematic Review and Meta-Analysis of Clinical Trials. 2021 Jul 20 1
4 31916186 Potential of Lipoprotein(a)-Lowering Strategies in Treating Coronary Artery Disease. 2020 Feb 2
5 32324598 The next generation of triglyceride-lowering drugs: will reducing apolipoprotein C-III or angiopoietin like protein 3 reduce cardiovascular disease? 2020 Jun 1
6 30500603 Safety and efficacy of mipomersen in patients with heterozygous familial hypercholesterolemia. 2019 Jan 1
7 30526168 Mipomersen and its use in familial hypercholesterolemia. 2019 Feb 1
8 31111240 Antisense Oligonucleotides Targeting Lipoprotein(a). 2019 May 20 3
9 31449975 A new dawn for managing dyslipidemias: The era of rna-based therapies. 2019 Dec 1
10 30293969 Effects of mipomersen, an apolipoprotein B100 antisense, on lipoprotein (a) metabolism in healthy subjects. 2018 Dec 1
11 26819195 Complex effects of inhibiting hepatic apolipoprotein B100 synthesis in humans. 2016 Jan 27 2
12 27261867 My Approach to the Patient With Familial Hypercholesterolemia. 2016 Jun 1
13 27578117 Pediatric experience with mipomersen as adjunctive therapy for homozygous familial hypercholesterolemia. 2016 Jul-Aug 2
14 27678436 Ten years of lipoprotein apheresis for familial hypercholesterolemia in Malaysia: A creative approach by a cardiologist in a developing country. 2016 Sep-Oct 1
15 27749370 Recent explanatory trials of the mode of action of drug therapies on lipoprotein metabolism. 2016 Dec 3
16 27919344 JCL roundtable: Risk evaluation and mitigation strategy. 2016 Nov - Dec 1
17 28018102 Apolipoprotein B100 is required for hepatitis C infectivity and Mipomersen inhibits hepatitis C. 2016 Dec 7 1
18 30695320 [Familial Hypercholesterolemia and Its Related Molecules]. 2016 Jun 1
19 25398643 The role of antisense oligonucleotide therapy in patients with familial hypercholesterolemia: risks, benefits, and management recommendations. 2015 Jan 1
20 25410046 Lipoprotein apheresis in the management of familial hypercholesterolaemia: historical perspective and recent advances. 2015 Jan 1
21 25542072 Genetic therapies to lower cholesterol. 2015 Jan 1
22 25670911 The genetics of familial hypercholesterolemia and emerging therapies. 2015 1
23 25911076 Mipomersen preferentially reduces small low-density lipoprotein particle number in patients with hypercholesterolemia. 2015 Mar-Apr 1
24 25922802 New drugs for treating dyslipidemia: beyond statins. 2015 Apr 4
25 26370207 Challenges in the Diagnosis and Treatment of Homozygous Familial Hypercholesterolemia. 2015 Oct 1
26 26402926 Pharmacogenetics in the Development of Lipid Lowering Medications: Lomitapide & Mipomersen in Clinical Practice. 2015 Aug 1
27 24632267 The severe hypercholesterolemia phenotype: clinical diagnosis, management, and emerging therapies. 2014 May 20 1
28 24953393 Hypolipidaemic drug treatment: yesterday is not gone yet, today is challenging and tomorrow is coming soon; let us combine them all. 2014 1
29 25499943 Liver histology during Mipomersen therapy for severe hypercholesterolemia. 2014 Nov-Dec 1
30 23013161 Clinical pharmacological properties of mipomersen (Kynamro), a second generation antisense inhibitor of apolipoprotein B. 2013 Aug 1
31 23129439 LDL Lowering After Acute Coronary Syndrome: Is Lower Better? 2013 Feb 2
32 23314926 Therapeutic gene targeting approaches for the treatment of dyslipidemias and atherosclerosis. 2013 Apr 1
33 23319054 Exon skipping of hepatic APOB pre-mRNA with splice-switching oligonucleotides reduces LDL cholesterol in vivo. 2013 Mar 3
34 23461430 Management of familial hypercholesterolemia: a review of the recommendations from the National Lipid Association Expert Panel on Familial Hypercholesterolemia. 2013 Mar 2
35 23839331 Recent advances in the treatment of homozygous familial hypercholesterolaemia. 2013 Aug 1
36 23913122 New therapies targeting apoB metabolism for high-risk patients with inherited dyslipidaemias: what can the clinician expect? 2013 Dec 1
37 24013058 Mipomersen, an apolipoprotein B synthesis inhibitor, reduces atherogenic lipoproteins in patients with severe hypercholesterolemia at high cardiovascular risk: a randomized, double-blind, placebo-controlled trial. 2013 Dec 10 1
38 22301884 Antisense inhibition of apoB synthesis with mipomersen reduces plasma apoC-III and apoC-III-containing lipoproteins. 2012 Apr 1
39 22701100 Mipomersen: evidence-based review of its potential in the treatment of homozygous and severe heterozygous familial hypercholesterolemia. 2012 1
40 22799743 Therapeutic potential of mipomersen in the management of familial hypercholesterolaemia. 2012 Jul 30 1
41 23152839 Randomized, placebo-controlled trial of mipomersen in patients with severe hypercholesterolemia receiving maximally tolerated lipid-lowering therapy. 2012 1
42 23226021 Mipomersen and other therapies for the treatment of severe familial hypercholesterolemia. 2012 1
43 21210756 Mipomersen, an antisense apolipoprotein B synthesis inhibitor. 2011 Feb 1
44 21343632 Antisense oligonucleotide reduction of apoB-ameliorated atherosclerosis in LDL receptor-deficient mice. 2011 May 2
45 20425272 Development of apolipoprotein B antisense molecules as a therapy for hyperlipidemia. 2010 Jan 2
46 20508521 Apolipoprotein B synthesis inhibition: results from clinical trials. 2010 Aug 1
47 20615897 Short locked nucleic acid antisense oligonucleotides potently reduce apolipoprotein B mRNA and serum cholesterol in mice and non-human primates. 2010 Nov 2
48 21122677 Novel therapies and new targets of treatment for familial hypercholesterolemia. 2010 Sep-Oct 1
49 19056355 Cross-species comparison of in vivo PK/PD relationships for second-generation antisense oligonucleotides targeting apolipoprotein B-100. 2009 Mar 1 1
50 20129365 Current strategies and recent advances in the therapy of hypercholesterolemia. 2009 Dec 29 1