Title : Exon skipping of hepatic APOB pre-mRNA with splice-switching oligonucleotides reduces LDL cholesterol in vivo.

Pub. Date : 2013 Mar

PMID : 23319054






3 Functional Relationships(s)
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1 Exon skipping of hepatic APOB pre-mRNA with splice-switching oligonucleotides reduces LDL cholesterol in vivo. Oligonucleotides apolipoprotein B Homo sapiens
2 We have developed a series of APOB-directed splice-switching oligonucleotides (SSOs) that cause the expression of APOB87, a truncated isoform of APOB100. Oligonucleotides apolipoprotein B Homo sapiens
3 We have developed a series of APOB-directed splice-switching oligonucleotides (SSOs) that cause the expression of APOB87, a truncated isoform of APOB100. Oligonucleotides apolipoprotein B Homo sapiens