Sulfur

cytochrome P450 family 2 subfamily C member 9 ; Homo sapiens







34 Article(s)
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1 28992765 Phenotyping of CYP 4501A2 Activity by Total Overnight Salivary Caffeine Assessment (TOSCA) in Patients on Warfarin Treatment: A Cross-Sectional Study. 2018 Sep 1
2 27539372 CYP2C9 Genotype-Dependent Warfarin Pharmacokinetics: Impact of CYP2C9 Genotype on R- and S-Warfarin and Their Oxidative Metabolites. 2017 Mar 1
3 27763679 Theory-based pharmacokinetics and pharmacodynamics of S- and R-warfarin and effects on international normalized ratio: influence of body size, composition and genotype in cardiac surgery patients. 2017 Apr 1
4 26677906 In vitro inhibition and enhancement of liver microsomal S-777469 metabolism by long-chain fatty acids and serum albumin: insight into in vitro and in vivo discrepancy of metabolite formation in humans. 2016 1
5 25986145 Warfarin Metabolites in Patients Following Cardiac Valve Implantation: A Contribution of Clinical and Genetic Factors. 2015 Jun 1
6 24944083 Identification of human cytochrome P450 isozymes involved in the metabolism of naftopidil enantiomers in vitro. 2014 Nov 1
7 23641937 Quantum mechanics/molecular mechanics modeling of regioselectivity of drug metabolism in cytochrome P450 2C9. 2013 May 29 2
8 24023924 Distal effect of amino acid substitutions in CYP2C9 polymorphic variants causes differences in interatomic interactions against (S)-warfarin. 2013 1
9 22270321 Population pharmacokinetic modelling of S-warfarin to evaluate the design of drug-drug interaction studies for CYP2C9. 2012 Apr 1
10 22436668 Simultaneous determination of fluoxetine and norfluoxetine enantiomers using isotope discrimination mass spectroscopy solution method and its application in the CYP2C9-mediated stereoselective interactions. 2012 May 4 2
11 22752007 Comparison of metabolism of sesamin and episesamin by drug-metabolizing enzymes in human liver. 2012 Oct 1
12 21968795 Fenofibrate-induced decrease of expression of CYP2C11 and CYP2C6 in rat. 2011 Nov 1
13 20429590 Hydroxywarfarin metabolites potently inhibit CYP2C9 metabolism of S-warfarin. 2010 May 17 1
14 19464879 R(+)XK469 inhibits hydroxylation of S-warfarin by CYP2C9. 2009 Jul 1
15 20167000 New insights into the structural features and functional relevance of human cytochrome P450 2C9. Part II. 2009 Dec 1
16 18576910 Possible antiretroviral therapy-warfarin drug interaction. 2008 Jul 1
17 17960328 Effective virtual screening protocol for CYP2C9 ligands using a screening site constructed from flurbiprofen and S-warfarin pockets. 2007 Sep 1
18 16946524 Effect of glimepiride and glibenclamide on S-warfarin 7-hydroxylation by human liver microsomes, recombinant human CYP2C9.1 and CYP2C9.3. 2006 Sep 2
19 15647404 Interaction of warfarin with drugs, natural substances, and foods. 2005 Feb 1
20 15983826 Effect of aprepitant on the pharmacokinetics and pharmacodynamics of warfarin. 2005 Jul 1
21 15128047 Effects of CYP2C9 polymorphisms on the pharmacokinetics of R- and S-phenprocoumon in healthy volunteers. 2004 Jan 1
22 15742978 Genetic polymorphisms of cytochrome P450 2C9 causing reduced phenprocoumon (S)-7-hydroxylation in vitro and in vivo. 2004 Sep 10
23 12621390 Population differences in S-warfarin metabolism between CYP2C9 genotype-matched Caucasian and Japanese patients. 2003 Mar 1
24 12920163 Inhibitory effect of glyburide on human cytochrome p450 isoforms in human liver microsomes. 2003 Sep 1
25 14641553 Clinical relevance of genetic polymorphisms in the human CYP2C9 gene. 2003 Nov 1
26 11794436 Major bleeding caused by warfarin in a genetically susceptible patient. 2002 Jan 1
27 12913403 Warfarin dose adjustments based on CYP2C9 genetic polymorphisms. 2002 Dec 1
28 11213860 Implications of cytochrome P450 2C9 polymorphism on warfarin metabolism and dosing. 2001 Feb 1
29 10870095 Inhibition of human cytochrome P450 isoforms in vitro by zafirlukast. 1999 Nov 1
30 9352571 Genetic association between sensitivity to warfarin and expression of CYP2C9*3. 1997 Oct 1
31 9526963 Warfarin analog inhibition of human CYP2C9-catalyzed S-warfarin 7-hydroxylation. 1997 Nov 15 1
32 8886617 Substrate probe for the mechanism of aromatic hydroxylation catalyzed by cytochrome P450. 1996 Sep 1
33 7574697 Molecular cloning, expression and characterization of an endogenous human cytochrome P450 arachidonic acid epoxygenase isoform. 1995 Sep 10 1
34 8333835 Gene structure and upstream regulatory regions of human CYP2C9 and CYP2C18. 1993 Jul 15 1