siponimod

cytochrome P450 family 2 subfamily C member 9 ; Homo sapiens







8 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 35426132 The Impact of CYP2C9*11 Allelic Variant on the Pharmacokinetics of Phenytoin and (S)-Warfarin. 2022 Jul 1
2 35620290 Pharmacokinetic Characteristics of Siponimod in Healthy Volunteers and Patients With Multiple Sclerosis: Analyses of Published Clinical Trials. 2022 1
3 34109627 PharmVar GeneFocus: CYP2C9. 2021 Sep 1
4 30088221 Effect of Fluconazole Coadministration and CYP2C9 Genetic Polymorphism on Siponimod Pharmacokinetics in Healthy Subjects. 2019 Mar 9
5 31199498 Prediction of the Impact of Cytochrome P450 2C9 Genotypes on the Drug-Drug Interaction Potential of Siponimod With Physiologically-Based Pharmacokinetic Modeling: A Comprehensive Approach for Drug Label Recommendations. 2019 Nov 2
6 31392364 Siponimod pharmacokinetics, safety, and tolerability in combination with the potent CYP3A4 inhibitor itraconazole in healthy subjects with different CYP2C9 genotypes. 2019 Nov 2
7 29273968 In vitro studies and in silico predictions of fluconazole and CYP2C9 genetic polymorphism impact on siponimod metabolism and pharmacokinetics. 2018 Apr 12
8 30105453 Siponimod pharmacokinetics, safety, and tolerability in combination with rifampin, a CYP2C9/3A4 inducer, in healthy subjects. 2018 Dec 2