Tamoxifen

cytochrome P450 family 2 subfamily C member 9 ; Homo sapiens







15 Article(s)
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1 34199712 Effect of Genetic Variability in 20 Pharmacogenes on Concentrations of Tamoxifen and Its Metabolites. 2021 Jun 4 1
2 31785970 Cytochrome P450 2C9 polymorphism: Effect of amino acid substitutions on protein flexibility in the presence of tamoxifen. 2020 Feb 10
3 27198207 Multigene and Drug Interaction Approach for Tamoxifen Metabolite Patterns Reveals Possible Involvement of CYP2C9, CYP2C19, and ABCB1. 2016 Dec 1
4 25618289 Individualization of tamoxifen therapy: much more than just CYP2D6 genotyping. 2015 Mar 1
5 25940823 Effects of Pharmacogenetics on the Pharmacokinetics and Pharmacodynamics of Tamoxifen. 2015 Aug 1
6 23604525 Characterization of the biotransformation pathways of clomiphene, tamoxifen and toremifene as assessed by LC-MS/(MS) following in vitro and excretion studies. 2013 Jun 1
7 21480951 Impact of CYP2D6, CYP3A5, CYP2C9 and CYP2C19 polymorphisms on tamoxifen pharmacokinetics in Asian breast cancer patients. 2011 May 1
8 21906462 The clinical effectiveness and cost-effectiveness of genotyping for CYP2D6 for the management of women with breast cancer treated with tamoxifen: a systematic review. 2011 Sep 1
9 21152245 Novel pathway analysis of genomic polymorphism-cancer risk interaction in the Breast Cancer Prevention Trial. 2010 1
10 19843839 Safety of concomitant tamoxifen and warfarin. 2009 Nov 1
11 17024799 Tamoxifen inhibits cytochrome P450 2C9 activity in breast cancer patients. 2006 Aug 6
12 14642736 Biotransformation of tamoxifen in a human endometrial explant culture model. 2003 Dec 15 2
13 14678248 Oxidative metabolism of tamoxifen to Z-4-hydroxy-tamoxifen by cytochrome P450 isoforms: an appraisal of in vitro studies. 2003 Nov 1
14 12207635 The influence of CYP2B6, CYP2C9 and CYP2D6 genotypes on the formation of the potent antioestrogen Z-4-hydroxy-tamoxifen in human liver. 2002 Aug 1
15 8681455 The metabolism of tamoxifen by human cytochromes P450 is rationalized by molecular modelling of the enzyme-substrate interactions: potential importance to its proposed anti-carcinogenic/carcinogenic actions. 1996 Jun 1