Title : The clinical effectiveness and cost-effectiveness of genotyping for CYP2D6 for the management of women with breast cancer treated with tamoxifen: a systematic review.

Pub. Date : 2011 Sep

PMID : 21906462






1 Functional Relationships(s)
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1 TAM is known to be metabolised to its active metabolites N-desmethyl TAM and 4-hydroxytamoxifen by a number of CYP450 enzymes, including CYP2D6, CYP3A4, CYP2C9, CYP2C19 and CYP2B6. Tamoxifen cytochrome P450 family 2 subfamily C member 9 Homo sapiens