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35062050 | CYP450 drug inducibility in NAFLD via an in vitro hepatic model: Understanding drug-drug interactions in the fatty liver. | 2022 Feb |
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35370222 | Effects of Concomitant Administration of PXR Ligand Drugs on the Anticoagulant Effects of Warfarin. | 2022 Jun 1 |
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33542643 | Genetic Polymorphism Effect on Warfarin-Rifampin Interaction: A Case Report and Review of Literature. | 2021 |
1 |
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34872459 | Study on the associations between liver damage and antituberculosis drug rifampicin and relative metabolic enzyme gene polymorphisms. | 2021 Dec |
1 |
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31420941 | Expanded Physiologically-Based Pharmacokinetic Model of Rifampicin for Predicting Interactions With Drugs and an Endogenous Biomarker via Complex Mechanisms Including Organic Anion Transporting Polypeptide 1B Induction. | 2019 Nov |
1 |
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31676845 | Rapid maturation of the hepatic cell line Huh7 via CDK inhibition for PXR dependent CYP450 metabolism and induction. | 2019 Nov 1 |
1 |
| 7 |
29368402 | Comprehensive PBPK Model of Rifampicin for Quantitative Prediction of Complex Drug-Drug Interactions: CYP3A/2C9 Induction and OATP Inhibition Effects. | 2018 Mar |
1 |
| 8 |
29569712 | Cytochrome P450 3A Induction Predicts P-glycoprotein Induction; Part 2: Prediction of Decreased Substrate Exposure After Rifabutin or Carbamazepine. | 2018 Dec |
2 |
| 9 |
30105453 | Siponimod pharmacokinetics, safety, and tolerability in combination with rifampin, a CYP2C9/3A4 inducer, in healthy subjects. | 2018 Dec |
2 |
| 10 |
28157069 | Delayed de-induction of CYP2C9 compared to CYP3A after discontinuation of rifampicin: Report of two cases
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3 |
| 11 |
28173639 | Bosentan and Rifampin Interactions Modulate Influx Transporter and Cytochrome P450 Expression and Activities in Primary Human Hepatocytes. | 2017 May 1 |
1 |
| 12 |
26549688 | Transcription regulation of nuclear receptor PXR: Role of SUMO-1 modification and NDSM in receptor function. | 2016 Jan 15 |
1 |
| 13 |
26658225 | Application of Micropatterned Cocultured Hepatocytes to Evaluate the Inductive Potential and Degradation Rate of Major Xenobiotic Metabolizing Enzymes. | 2016 Feb |
1 |
| 14 |
26759747 | Rifampin-warfarin interaction in a mitral valve replacement patient receiving rifampin for infective endocarditis: a case report. | 2016 |
1 |
| 15 |
25335408 | [Polymorphism of the biotransformation gene--cytochrome-450 2C9 in the patients with tuberculosis]. | 2014 |
2 |
| 16 |
23852652 | Effects of cytochrome P450 inhibitors and inducers on the metabolism and pharmacokinetics of ospemifene. | 2013 Oct |
1 |
| 17 |
23974699 | Chronological effects of rifampicin discontinuation on cytochrome P450 activity in healthy Japanese volunteers, using the cocktail method. | 2013 Dec |
1 |
| 18 |
21292004 | NCOA6 differentially regulates the expression of the CYP2C9 and CYP3A4 genes. | 2011 May |
1 |
| 19 |
21930825 | Complex drug interactions of HIV protease inhibitors 2: in vivo induction and in vitro to in vivo correlation of induction of cytochrome P450 1A2, 2B6, and 2C9 by ritonavir or nelfinavir. | 2011 Dec |
1 |
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20086032 | Hepatocyte nuclear factor 4{alpha} regulates rifampicin-mediated induction of CYP2C genes in primary cultures of human hepatocytes. | 2010 Apr |
3 |
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19202563 | Regulation of cytochrome P450 2C9 expression in primary cultures of human hepatocytes. | 2009 Jan-Feb |
2 |
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19369937 | Relative impact of genotype and enzyme induction on the metabolic capacity of CYP2C9 in healthy volunteers. | 2009 Jul |
1 |
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19515014 | Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. | 2009 |
2 |
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15676042 | Influence of rifampicin on the expression and function of human intestinal cytochrome P450 enzymes. | 2005 Feb |
2 |
| 25 |
15919766 | The nuclear receptors constitutive androstane receptor and pregnane X receptor cross-talk with hepatic nuclear factor 4alpha to synergistically activate the human CYP2C9 promoter. | 2005 Sep |
2 |
| 26 |
14600250 | Induction of human CYP2C9 by rifampicin, hyperforin, and phenobarbital is mediated by the pregnane X receptor. | 2004 Feb |
8 |
| 27 |
14722322 | Induction of drug metabolism enzymes and MDR1 using a novel human hepatocyte cell line. | 2004 Apr |
1 |
| 28 |
15001966 | Effect of rifampin on the pharmacokinetics of rosiglitazone in healthy subjects. | 2004 Mar |
1 |
| 29 |
15364537 | The effects of gender, age, ethnicity, and liver cirrhosis on cytochrome P450 enzyme activity in human liver microsomes and inducibility in cultured human hepatocytes. | 2004 Sep 15 |
1 |
| 30 |
12882588 | Pharmacokinetic interactions with rifampicin : clinical relevance. | 2003 |
1 |
| 31 |
14534520 | Effect of rifampin on the pharmacokinetics and pharmacodynamics of gliclazide. | 2003 Oct |
1 |
| 32 |
11679585 | Transcriptional regulation of CYP2C9 gene. Role of glucocorticoid receptor and constitutive androstane receptor. | 2002 Jan 4 |
2 |
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12130704 | Expression and induction of CYP2C P450 enzymes in primary cultures of human hepatocytes. | 2002 Aug |
1 |
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12426514 | Rifampin markedly decreases plasma concentrations of praziquantel in healthy volunteers. | 2002 Nov |
2 |
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11181490 | Induction of CYP2C genes in human hepatocytes in primary culture. | 2001 Mar |
4 |
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11406737 | Effects of rifampin on the pharmacokinetics and pharmacodynamics of glyburide and glipizide. | 2001 Jun |
1 |
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11714868 | Rifampin is a selective, pleiotropic inducer of drug metabolism genes in human hepatocytes: studies with cDNA and oligonucleotide expression arrays. | 2001 Dec |
1 |
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11735605 | Pharmacokinetic aspects of treating infections in the intensive care unit: focus on drug interactions. | 2001 |
1 |
| 39 |
10673364 | Quantitative analysis of constitutive and inducible CYPs mRNA expression in the HepG2 cell line using reverse transcription-competitive PCR. | 2000 Jan 27 |
1 |
| 40 |
10924340 | Interleukin-6 negatively regulates the expression of pregnane X receptor and constitutively activated receptor in primary human hepatocytes. | 2000 Aug 11 |
1 |
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11136298 | Effect of rifampicin on the pharmacokinetics and pharmacodynamics of glimepiride. | 2000 Dec |
2 |
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9663807 | Cytochrome P4502C9: an enzyme of major importance in human drug metabolism. | 1998 Jun |
1 |
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9010637 | Identification of cytochromes P450 involved in the human liver microsomal metabolism of the thromboxane A2 inhibitor seratrodast (ABT-001). | 1997 Jan |
1 |
| 44 |
7614688 | Cytochromes P450 in cynomolgus monkeys mutagenically activate 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) but not 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx). | 1995 Jul |
2 |
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2200675 | Expression of cytochrome P-450 enzymes in cultured human hepatocytes. | 1990 Jul 31 |
1 |
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20702214 | Effects of various inducers on the expression of cytochromes P-450 IIC8, 9, 10 and IIIA in cultured adult human hepatocytes. | 1990 |
1 |