Mitoxantrone

Pim-1 proto-oncogene, serine/threonine kinase ; Homo sapiens







5 Article(s)
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1 27374090 Pim kinase inhibition sensitizes FLT3-ITD acute myeloid leukemia cells to topoisomerase 2 inhibitors through increased DNA damage and oxidative stress. 2016 Jul 26 2
2 26351135 Overcoming ABCG2-mediated drug resistance with imidazo-[1,2-b]-pyridazine-based Pim1 kinase inhibitors. 2015 Oct 1
3 23442188 A new target for an old drug: identifying mitoxantrone as a nanomolar inhibitor of PIM1 kinase via kinome-wide selectivity modeling. 2013 Mar 28 6
4 18056989 The 44-kDa Pim-1 kinase phosphorylates BCRP/ABCG2 and thereby promotes its multimerization and drug-resistant activity in human prostate cancer cells. 2008 Feb 8 1
5 9853146 Percutaneous mitoxantrone injection for primary and secondary liver tumors: preliminary results. 1998 Sep-Oct 1