Atorvastatin

3-hydroxy-3-methylglutaryl-CoA reductase ; Rattus norvegicus







29 Article(s)
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1 33755739 Role of inflammatory, oxidative, and ER stress signaling in the neuroprotective effect of atorvastatin against doxorubicin-induced cognitive impairment in rats. 2021 Jul 2
2 32395205 The preventive effect of atorvastatin on liver fibrosis in the bile duct ligation rats via antioxidant activity and down-regulation of Rac1 and NOX1. 2020 Jan 1
3 29164519 Atorvastatin Prevents Early Oxidative Events and Modulates Inflammatory Mediators in the Striatum Following Intranasal 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) Administration in Rats. 2018 Apr 1
4 29775891 Protective effect of atorvastatin meditated by HMGCR gene on diabetic rats with atherosclerosis: An in vivo and in vitro study. 2018 Aug 2
5 29950080 [Effect of Huangqi San on AMPK/ACC/CPT1 pathway in hyperlipidemia rats]. 2018 Jun 1
6 28295458 Improvement in erectile function in a rat model of high cholesterol diet-induced atherosclerosis by atorvastatin in a manner that is independent of its lipid-lowering property. 2017 Nov 1
7 27727327 Amelioration of Renal Inflammation, Endoplasmic Reticulum Stress and Apoptosis Underlies the Protective Effect of Low Dosage of Atorvastatin in Gentamicin-Induced Nephrotoxicity. 2016 1
8 25874913 Atorvastatin prevents neuroinflammation in chronic constriction injury rats through nuclear NFκB downregulation in the dorsal root ganglion and spinal cord. 2015 Jun 17 1
9 25933963 Effect of atorvastatin, a HMG-CoA reductase inhibitor in monosodium iodoacetate-induced osteoarthritic pain: implication for osteoarthritis therapy. 2015 Jun 2
10 23002242 FOXO1 impairs whereas statin protects endothelial function in diabetes through reciprocal regulation of Kruppel-like factor 2. 2013 Jan 1 1
11 24130702 Atorvastatin decreases bone loss, inflammation and oxidative stress in experimental periodontitis. 2013 1
12 24369464 Cholesterol Contributes to Diabetic Nephropathy through SCAP-SREBP-2 Pathway. 2013 1
13 21709429 Effects of HMG-CoA reductase inhibitors on the pharmacokinetics of losartan and its main metabolite EXP-3174 in rats: possible role of CYP3A4 and P-gp inhibition by HMG-CoA reductase inhibitors. 2011 1
14 22615676 Renoprotective effects of combining ACE inhibitors and statins in experimental diabetic rats. 2011 1
15 20936696 p120 catenin/αN-catenin are molecular targets in the neuroprotection and neuronal plasticity mediated by atorvastatin after focal cerebral ischemia. 2010 Dec 2
16 19577561 Swertiamarin: a lead from Enicostemma littorale Blume. for anti-hyperlipidaemic effect. 2009 Sep 1 1
17 18817622 Tissue-specific effects of atorvastatin on 3-hydroxy-3-methylglutarylcoenzyme A reductase expression and activity in spontaneously hypertensive rats. 2008 Oct 2
18 17328247 Effect of atorvastatin on the pharmacokinetics of diltiazem and its main metabolite, desacetyldiltiazem, in rats. 2007 Jan 1
19 16242301 Effects of atorvastatin on the Th1/Th2 polarization of ongoing experimental autoimmune myocarditis in Lewis rats. 2005 Dec 1
20 15166393 HMG-CoA reductase inhibitor, atorvastatin, promotes sensorimotor recovery, suppressing acute inflammatory reaction after experimental intracerebral hemorrhage. 2004 Jul 1
21 15191412 Anti-apoptotic effect of atorvastatin, a 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor, on cardiac myocytes through protein kinase C activation. 2004 May-Jun 1
22 15538290 Atorvastatin ameliorates renal tissue damage in unilateral ureteral obstruction. 2004 Dec 1
23 12783420 Statins induce angiogenesis, neurogenesis, and synaptogenesis after stroke. 2003 Jun 1
24 12056585 High doses of atorvastatin and simvastatin induce key enzymes involved in VLDL production. 2002 May 1
25 12898835 The eye lens evaluation of the atorvastatin-treated white rat. 2002 1
26 9469588 Atorvastatin action involves diminished recovery of hepatic HMG-CoA reductase activity. 1998 Jan 4
27 9485553 Development, validation, and interlaboratory comparison of an HMG-CoA reductase inhibition assay for quantitation of atorvastatin in plasma matrices. 1998 Feb 1
28 8921332 Fertility and general reproduction studies in rats with the HMG-CoA reductase inhibitor, atorvastatin. 1996 Aug 1
29 7778043 Developmental toxicity of the HMG-CoA reductase inhibitor, atorvastatin, in rats and rabbits. 1994 Dec 1