Title : Amelioration of Renal Inflammation, Endoplasmic Reticulum Stress and Apoptosis Underlies the Protective Effect of Low Dosage of Atorvastatin in Gentamicin-Induced Nephrotoxicity.

Pub. Date : 2016

PMID : 27727327






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Since atorvastatin, 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors, exerts lipid-lowering effects, antioxidant, anti-inflammatory as well as anti-apoptotic effects, this study aimed to investigate the protective effects of atorvastatin against gentamicin-induced nephrotoxicity. Atorvastatin 3-hydroxy-3-methylglutaryl-CoA reductase Rattus norvegicus