Arginine

von Willebrand factor ; Homo sapiens







43 Article(s)
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1 25690668 von Willebrand factor arginine 1205 substitution results in accelerated macrophage-dependent clearance in vivo. 2015 May 1
2 22490677 Sequence and structure relationships within von Willebrand factor. 2012 Jul 12 1
3 20075158 Amino acid residues Arg(659), Arg(660), and Tyr(661) in the spacer domain of ADAMTS13 are critical for cleavage of von Willebrand factor. 2010 Mar 18 5
4 18492952 Extensive contacts between ADAMTS13 exosites and von Willebrand factor domain A2 contribute to substrate specificity. 2008 Sep 1 1
5 18502798 Mechanistic studies on ADAMTS13 catalysis. 2008 Sep 2
6 17146059 Exosite interactions contribute to tension-induced cleavage of von Willebrand factor by the antithrombotic ADAMTS13 metalloprotease. 2006 Dec 12 1
7 15975930 The proximal carboxyl-terminal domains of ADAMTS13 determine substrate specificity and are all required for cleavage of von Willebrand factor. 2005 Aug 19 1
8 15571600 Gastrointestinal angiodysplasia in a patient with type 2 von Willebrand's disease and analysis of exon 28 of the von Willebrand factor gene. 2004 Dec 1
9 12855711 A consensus tetrapeptide selected by phage display adopts the conformation of a dominant discontinuous epitope of a monoclonal anti-VWF antibody that inhibits the von Willebrand factor-collagen interaction. 2003 Sep 26 1
10 11150026 Type 2M von Willebrand disease variant characterized by abnormal von willebrand factor multimerization. 2001 Jan 2
11 11159522 The arginine-552-cysteine (R1315C) mutation within the A1 loop of von Willebrand factor induces an abnormal folding with a loss of function resulting in type 2A-like phenotype of von Willebrand disease: study of 10 patients and mutated recombinant von Willebrand factor. 2001 Feb 15 2
12 11920243 Selective inactivation of Von Willebrand factor binding to glycoprotein IIb/IIIa and to inhibitor monoclonal antibody 9 by site-directed mutagenesis. 2001 1
13 10739395 Protamine sulphate inhibits platelet membrane glycoprotein Ib-von Willebrand factor activity. 2000 Feb 1
14 10845886 Platelet thrombus formation on collagen at high shear rates is mediated by von Willebrand factor-glycoprotein Ib interaction and inhibited by von Willebrand factor-glycoprotein IIb/IIIa interaction. 2000 Jun 1
15 9792286 Type 2N von Willebrand disease due to Arg91Gln substitution and a cytosine deletion in exon 18 of the von Willebrand factor gene. 1998 Oct 2
16 9808586 Interaction of sickle erythrocytes with endothelial cells in the presence of endothelial cell conditioned medium induces oxidant stress leading to transendothelial migration of monocytes. 1998 Nov 15 1
17 9845532 A novel mutation in the D3 domain of von Willebrand factor markedly decreases its ability to bind factor VIII and affects its multimerization. 1998 Dec 15 1
18 9858249 Identification of new type 2B von Willebrand disease mutations: Arg543Gln, Arg545Pro and Arg578Leu. 1998 Dec 2
19 8622978 Defective dimerization of von Willebrand factor subunits due to a Cys-> Arg mutation in type IID von Willebrand disease. 1996 Apr 16 1
20 8839833 Dominant type 1 von Willebrand disease caused by mutated cysteine residues in the D3 domain of von Willebrand factor. 1996 Oct 1 1
21 7620154 Identification of two mutations (Arg611Cys and Arg611His) in the A1 loop of von Willebrand factor (vWF) responsible for type 2 von Willebrand disease with decreased platelet-dependent function of vWF. 1995 Aug 1 1
22 7974349 Epitope mapping of inhibitory monoclonal antibodies to human von Willebrand factor by using recombinant cDNA libraries. 1994 Jun 2
23 8483792 Synthetic peptides inhibit the interaction of von Willebrand factor-platelet membrane glycoproteins. 1993 Mar-Apr 3
24 1323869 [The glycoprotein IIb/IIIa complex of the platelets. An activation-dependent integrin]. 1992 Feb 2
25 1370885 Comparison of the primary structure of the functional domains of human and porcine von Willebrand factor that mediate platelet adhesion. 1992 Jan 31 1
26 1419804 Defects in type IIA von Willebrand disease: a cysteine 509 to arginine substitution in the mature von Willebrand factor disrupts a disulphide loop involved in the interaction with platelet glycoprotein Ib-IX. 1992 Sep 3
27 1569181 Factor VIII-East Hartford (arginine 1689 to cysteine) has procoagulant activity when separated from von Willebrand factor. 1992 May 1
28 1571548 Preferred sequence requirements for cleavage of pro-von Willebrand factor by propeptide-processing enzymes. 1992 May 1 1
29 1732004 The mutation Arg (53)----Trp causes von Willebrand disease Normandy by abolishing binding to factor VIII. Studies with recombinant von Willebrand factor. 1992 Feb 1 2
30 1737795 Selective inactivation of the Arg-Gly-Asp-Ser (RGDS) binding site in von Willebrand factor by site-directed mutagenesis. 1992 Feb 15 1
31 1720019 A modified Arg-Asp-Val (RDV) peptide derived during the synthesis of Arg-Glu-Asp-Val (REDV), a tetrapeptide derived from an alternatively spliced site in fibronectin, inhibits the binding of fibrinogen, fibronectin, von Willebrand factor and vitronectin to activated platelets. 1991 Oct 31 2
32 1871720 Platelets adhere to sulfatides by von Willebrand factor dependent and independent mechanisms. 1991 May 6 1
33 1715119 Multiple epitope specificity of monoclonal antibodies to a single synthetic peptide: use in the characterization of the GP IIb-IIIa binding domain of von Willebrand factor. 1990 3
34 2545728 Von Willebrand factor promotes endothelial cell adhesion via an Arg-Gly-Asp-dependent mechanism. 1989 Jul 4
35 2688759 Molecular cloning, expression and assembly of multimeric von Willebrand factor. 1989 Oct 1
36 2453507 Generation and characterization of peptide-specific antibodies that inhibit von Willebrand factor binding to glycoprotein IIb-IIIa without interacting with other adhesive molecules. Selectivity is conferred by Pro1743 and other amino acid residues adjacent to the sequence Arg1744-Gly1745-Asp1746. 1988 Jun 5 3
37 3131331 Proteolytic cleavage of the precursor of von Willebrand factor is not essential for multimer formation. 1988 Jun 15 1
38 2447074 Biosynthetic and functional properties of an Arg-Gly-Asp-directed receptor involved in human melanoma cell attachment to vitronectin, fibrinogen, and von Willebrand factor. 1987 Dec 25 1
39 3037722 Inhibition of von Willebrand factor binding to platelets by two recognition site peptides: the pentadecapeptide of the carboxy terminus of the fibrinogen gamma chain and the tetrapeptide arg-gly-asp-ser. 1987 May 1 1
40 3500868 The dualistic mechanisms of platelet adhesion to von Willebrand factor substrates. 1987 Dec 1
41 2944746 Identification of two distinct regions within the binding sites for fibrinogen and fibronectin on the IIb-IIIa human platelet membrane glycoprotein complex by monoclonal antibodies P2 and P4. 1986 Sep 15 3
42 3019665 Full-length von Willebrand factor (vWF) cDNA encodes a highly repetitive protein considerably larger than the mature vWF subunit. 1986 Aug 1
43 2864688 Cloning and characterization of two cDNAs coding for human von Willebrand factor. 1985 Oct 1