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33957567 | Physiological functions and therapeutic applications of neutral sphingomyelinase and acid sphingomyelinase. | 2021 Jul |
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34089907 | Characterization of neutral sphingomyelinase activity and isoform expression in rodent skeletal muscle mitochondria. | 2021 Jul |
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34770770 | Alterations in β-Cell Sphingolipid Profile Associated with ER Stress and iPLA2β: Another Contributor to β-Cell Apoptosis in Type 1 Diabetes. | 2021 Oct 21 |
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32028642 | NADPH Oxidase-Mediated Activation of Neutral Sphingomyelinase Is Responsible for Diesel Particulate Extract-Induced Keratinocyte Apoptosis. | 2020 Feb 3 |
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30106227 | Exosomal neutral sphingomyelinase 1 suppresses hepatocellular carcinoma via decreasing the ratio of sphingomyelin/ceramide. | 2018 Oct |
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30197917 | Data on cell survival, apoptosis, ceramide metabolism and oxidative stress in A-494 renal cell carcinoma cell line treated with hesperetin and hesperetin-7-O-acetate. | 2018 Oct |
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27077455 | Inhibition of neutral sphingomyelinase decreases elevated levels of nitrative and oxidative stress markers in liver ischemia-reperfusion injury. | 2017 Jul |
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28577326 | Trivalent chromium induces autophagy by activating sphingomyelin phosphodiesterase 2 and increasing cellular ceramide levels in renal HK2 cells. | 2017 Nov |
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26709664 | Inhibition of neutral sphingomyelinase protects mice against systemic tuberculosis. | 2016 Jan 1 |
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26843596 | Interleukin-1β activates an Src family kinase to stimulate the plasma membrane Ca2+ pump in hippocampal neurons. | 2016 Apr |
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27479697 | Role of sphingomyelinase in mitochondrial ceramide accumulation during reperfusion. | 2016 Oct |
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27556861 | Inhibition of interleukin-1β-induced endothelial tissue factor expression by the synthetic cannabinoid WIN 55,212-2. | 2016 Sep 20 |
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27980577 | New Aspects of Silibinin Stereoisomers and their 3-O-galloyl Derivatives on Cytotoxicity and Ceramide Metabolism in Hep G2 hepatocarcinoma Cell Line. | 2016 Summer |
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| 14 |
25168245 | Stress-induced ceramide generation and apoptosis via the phosphorylation and activation of nSMase1 by JNK signaling. | 2015 Feb |
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26046034 | Neutral sphingomyelinase and breast cancer research. | 2015 Apr |
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26079297 | Ceramide signalling impinges on Sit4p and Hog1p to promote mitochondrial fission and mitophagy in Isc1p-deficient cells. | 2015 Sep |
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| 17 |
26232616 | Ceramide generation during curcumin-induced apoptosis is controlled by crosstalk among Bcl-2, Bcl-xL, caspases and glutathione. | 2015 Nov |
4 |
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24650665 | Involvement of diacylglycerol produced by phospholipase D activation in Aβ-induced reduction of sAPPα secretion in SH-SY5Y neuroblastoma cells. | 2014 Apr 18 |
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24892004 | Inhibition of neutral sphingomyelinases in skeletal muscle attenuates fatty-acid induced defects in metabolism and stress. | 2014 |
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24982331 | Characterizing the sphingomyelinase pathway triggered by PRIMA-1 derivatives in lung cancer cells with differing p53 status. | 2014 Jul |
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24997497 | Activation of neutral-sphingomyelinase, MAPKs, and p75 NTR-mediating caffeic acid phenethyl ester-induced apoptosis in C6 glioma cells. | 2014 Jul 5 |
4 |
| 22 |
25240837 | Curcumin induces apoptosis of multidrug-resistant human leukemia HL60 cells by complex pathways leading to ceramide accumulation. | 2014 Dec |
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| 23 |
21862212 | Targeting the ceramide system in cancer. | 2013 May 28 |
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| 24 |
23065519 | Platelet protease-activated receptor (PAR)4, but not PAR1, associated with neutral sphingomyelinase responsible for thrombin-stimulated ceramide-NF-κB signaling in human platelets. | 2013 May |
1 |
| 25 |
23840630 | Identification of Heat Shock Protein 60 as a Regulator of Neutral Sphingomyelinase 2 and Its Role in Dopamine Uptake. | 2013 |
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| 26 |
24358176 | Ceramide mediates Ox-LDL-induced human vascular smooth muscle cell calcification via p38 mitogen-activated protein kinase signaling. | 2013 |
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| 27 |
22230689 | Ceramide kinase regulates TNFα-stimulated NADPH oxidase activity and eicosanoid biosynthesis in neuroblastoma cells. | 2012 Jun |
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22980406 | Bioeffects of ultrasound-stimulated microbubbles on endothelial cells: gene expression changes associated with radiation enhancement in vitro. | 2012 Nov |
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20378749 | An obligate role for membrane-associated neutral sphingomyelinase activity in orienting chemotactic migration of human neutrophils. | 2011 Feb |
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21490312 | Ceramide inhibits Kv currents and contributes to TP-receptor-induced vasoconstriction in rat and human pulmonary arteries. | 2011 Jul |
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21904434 | Molecular modeling of human neutral sphingomyelinase provides insight into its molecular interactions. | 2011 |
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19617631 | Myocardium of type 2 diabetic and obese patients is characterized by alterations in sphingolipid metabolic enzymes but not by accumulation of ceramide. | 2010 Jan |
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20071681 | Inhibition of cytokine signaling in human retinal endothelial cells through downregulation of sphingomyelinases by docosahexaenoic acid. | 2010 Jun |
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20378533 | Identification and characterization of murine mitochondria-associated neutral sphingomyelinase (MA-nSMase), the mammalian sphingomyelin phosphodiesterase 5. | 2010 Jun 4 |
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20456020 | Plasma membrane sphingomyelin hydrolysis increases hippocampal neuron excitability by sphingosine-1-phosphate mediated mechanisms. | 2010 Jul |
4 |
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20836852 | Withanolide D induces apoptosis in leukemia by targeting the activation of neutral sphingomyelinase-ceramide cascade mediated by synergistic activation of c-Jun N-terminal kinase and p38 mitogen-activated protein kinase. | 2010 Sep 13 |
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19531467 | Peptidoglycan induces cyclooxygenase-2 expression in macrophages by activating the neutral sphingomyelinase-ceramide pathway. | 2009 Jul 31 |
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18299447 | Mutations in the neutral sphingomyelinase gene SMPD3 implicate the ceramide pathway in human leukemias. | 2008 May 1 |
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18505924 | Neutral sphingomyelinase-3 is a DNA damage and nongenotoxic stress-regulated gene that is deregulated in human malignancies. | 2008 May |
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16822514 | MRI visualized neo-intimal dissection and co-localization of novel apoptotic markers apolipoprotein C-1, ceramide and caspase-3 in a Watanabe hyperlipidemic rabbit model. | 2007 Mar |
2 |
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16440306 | LDL induces Saos2 osteoblasts death via Akt pathways responsive to a neutral sphingomyelinase inhibitor. | 2006 Jun 1 |
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16499950 | Shift in sphingolipid metabolism leads to an accumulation of ceramide in senescence. | 2006 May |
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16517606 | Novel tumor necrosis factor-responsive mammalian neutral sphingomyelinase-3 is a C-tail-anchored protein. | 2006 May 12 |
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16524368 | Amyloid beta peptide increases DP5 expression via activation of neutral sphingomyelinase and JNK in oligodendrocytes. | 2006 May |
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16763091 | Penta-acetyl geniposide induce apoptosis in C6 glioma cells by modulating the activation of neutral sphingomyelinase-induced p75 nerve growth factor receptor and protein kinase Cdelta pathway. | 2006 Sep |
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16938269 | Neutral sphingomyelinases and nSMase2: bridging the gaps. | 2006 Dec |
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16981685 | The extended family of neutral sphingomyelinases. | 2006 Sep 26 |
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15642349 | Sphingomyelinase causes endothelium-dependent vasorelaxation through endothelial nitric oxide production without cytosolic Ca(2+) elevation. | 2005 Jan 17 |
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15741222 | Thalidomide-induced antiangiogenic action is mediated by ceramide through depletion of VEGF receptors, and is antagonized by sphingosine-1-phosphate. | 2005 Jul 1 |
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15749390 | Protective effects of S-nitrosoglutathione against amyloid beta-peptide neurotoxicity. | 2005 Apr 1 |
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