Benzo(a)pyrene

prohibitin 2 ; Mus musculus







52 Article(s)
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1 35567930 Benzo[a]pyrene exposure in muscle triggers sarcopenia through aryl hydrocarbon receptor-mediated reactive oxygen species production. 2022 May 11 1
2 33393179 Pinocembrin attenuates benzo(a)pyrene-induced CYP1A1 expression through multiple pathways: An in vitro and in vivo study. 2021 Apr 1
3 34332006 Benzo(a)pyrene exposure in utero exacerbates Parkinson's Disease (PD)-like α-synucleinopathy in A53T human alpha-synuclein transgenic mice. 2021 Sep 15 1
4 32684523 Benzo[a]pyrene injures BMP2-induced osteogenic differentiation of mesenchymal stem cells through AhR reducing BMPRII. 2020 Oct 15 1
5 30614051 Circular RNA microarray expression profile in 3,4-benzopyrene/angiotensin II-induced abdominal aortic aneurysm in mice. 2019 Jun 1
6 31240266 Paternal exposure to benzo(a)pyrene induces genome-wide mutations in mouse offspring. 2019 1
7 31679311 Anti-Inflammatory and Apoptotic Signaling Effect of Fucoxanthin on Benzo(A)Pyrene-Induced Lung Cancer in Mice. 2019 1
8 29368147 Cytochrome b 5 impacts on cytochrome P450-mediated metabolism of benzo[a]pyrene and its DNA adduct formation: studies in hepatic cytochrome b 5 /P450 reductase null (HBRN) mice. 2018 Apr 1
9 29482396 Effects of lactational exposure to low-dose BaP on allergic and non-allergic immune responses in mice offspring. 2018 Dec 1
10 29181036 Microarray Analysis Reveals a Potential Role of lncRNA Expression in 3,4-Benzopyrene/Angiotensin II-Activated Macrophage in Abdominal Aortic Aneurysm. 2017 1
11 26984301 Empirical analysis of BMD metrics in genetic toxicology part II: in vivo potency comparisons to promote reductions in the use of experimental animals for genetic toxicity assessment. 2016 May 1
12 25308545 Single cell gel electrophoresis (SCGE) and Pig-a mutation assay in vivo-tools for genotoxicity testing from a regulatory perspective: a study of benzo[a]pyrene in Ogg1(-/-) mice. 2014 Sep 15 1
13 25374376 Antigenotoxic capacity of beta-caryophyllene in mouse, and evaluation of its antioxidant and GST induction activities. 2014 1
14 23047765 Oral benzo[a]pyrene in Cyp1a1/1b1(-/-) double-knockout mice: Microarray analysis during squamous cell carcinoma formation in preputial gland duct. 2013 May 1 1
15 22759596 Exposure to benzo[a]pyrene of Hepatic Cytochrome P450 Reductase Null (HRN) and P450 Reductase Conditional Null (RCN) mice: Detection of benzo[a]pyrene diol epoxide-DNA adducts by immunohistochemistry and 32P-postlabelling. 2012 Sep 3 1
16 20188852 Lack of change in microRNA expression in adult mouse liver following treatment with benzo(a)pyrene despite robust mRNA transcriptional response. 2011 Jun 17 1
17 21827816 Combined effects of curcumin and piperine in ameliorating benzo(a)pyrene induced DNA damage. 2011 Nov 1
18 20422711 Benzo(a)pyrene causes PRKAA1/2-dependent ID2 loss in trophoblast stem cells. 2010 Jun 1
19 21137059 Deficiency of glycine N-methyltransferase results in deterioration of cellular defense to stress in mouse liver. 2010 Apr 1
20 19228760 Cigarette smoke causes follicle loss in mice ovaries at concentrations representative of human exposure. 2009 Jun 1
21 19409565 Overexpression of antioxidant enzymes in ApoE-deficient mice suppresses benzo(a)pyrene-accelerated atherosclerosis. 2009 Nov 1
22 17997381 Basal and inducible CYP1 mRNA quantitation and protein localization throughout the mouse gastrointestinal tract. 2008 Feb 15 2
23 18396263 Benzo[a]pyrene inhibits osteoclastogenesis by affecting RANKL-induced activation of NF-kappaB. 2008 May 15 1
24 19105532 Immunohistochemical study of fibrosis and adenocarcinoma in dominant-negative p53 transgenic mice exposed to chrysotile asbestos and benzo(a)pyrene. 2008 1
25 17397927 Modulation of behavior and NMDA-R1 gene mRNA expression in adult female mice after sub-acute administration of benzo(a)pyrene. 2007 May 1
26 17909032 Glutathione transferase pi plays a critical role in the development of lung carcinogenesis following exposure to tobacco-related carcinogens and urethane. 2007 Oct 1 1
27 15800929 Combined subcarcinogenic benzo[a]pyrene and UVA synergistically caused high tumor incidence and mutations in H-ras gene, but not p53, in SKH-1 hairless mouse skin. 2005 Aug 20 1
28 16392709 Effects of Japanese kelp (kombu) on life span of benzo[a]pyrene-fed mice. 2005 Oct 1
29 14578163 Effect of arsenic on benzo[a]pyrene DNA adduct levels in mouse skin and lung. 2004 Apr 1
30 15102951 Oral exposure to benzo[a]pyrene in the mouse: detoxication by inducible cytochrome P450 is more important than metabolic activation. 2004 May 1
31 15748481 [Effects of selenium on benzo[a] pyrene-induce DNA damage in mouse lung cells]. 2004 Dec 1
32 12884409 Resveratrol, a natural aryl hydrocarbon receptor antagonist, protects lung from DNA damage and apoptosis caused by benzo[a]pyrene. 2003 Jul-Aug 1
33 14556224 Development and characterization of a stable epithelial cell line from Muta Mouse lung. 2003 1
34 12034312 Arsenic co-exposure potentiates benzo[a]pyrene genotoxicity. 2002 May 27 1
35 11499694 Use of in vitro assays to assess hematotoxic effects of environmental compounds. 2001 1
36 11741297 Benzo[a]pyrene-induced toxicity: paradoxical protection in Cyp1a1(-/-) knockout mice having increased hepatic BaP-DNA adduct levels. 2001 Dec 21 3
37 10856296 DNA-damaging aryl hydrocarbons induce Mdm2 expression via p53-independent post-transcriptional mechanisms. 2000 Aug 25 1
38 10873718 Tumor promotion of N-nitroso-N-(3-keto-1, 2-butanediol)-3'-nitrotyramine derived from nitrosation of Maillard reaction product in CD-1 mice. 2000 Jul 1 1
39 8676899 Influence of benzylisothiocyanate and 13-cis-retinoic acid on micronucleus formation induced by benzo[a]pyrene. 1996 Jun 10 1
40 8804551 Effect of dietary restriction on benzo[a]pyrene (BaP) metabolic activation and pulmonary BaP-DNA adduct formation in mouse. 1996 1
41 8075628 Evaluation of frequency of micronuclei in exfoliated cells from bladder of mice treated with benzo(a) pyrene, 2-acetylaminofluorene and cyclophosphamide. 1994 Jun 1
42 8097600 Effects of benzo[a]pyrene on concanavalin A-stimulated human peripheral blood mononuclear cells in vitro: inhibition of proliferation but no effect on parameters related to the G1 phase of the cell cycle. 1993 Apr 1
43 1412470 Evaluation of murine splenic cell type metabolism of benzo[a]pyrene and functionality in vitro following repeated in vivo exposure to benzo[a]pyrene. 1992 Oct 1
44 2778258 Complex mixture effects on the dermal absorption of benzo[a]pyrene and other polycyclic aromatic hydrocarbons from mouse skin. 1989 Aug 1
45 2835829 Suppression of splenic lymphocyte function by 7,12-dimethylbenz[a]anthracene (DMBA) in vitro. 1988 May 1
46 3131261 Inhibition of IL-2 responsiveness following exposure to benzo(a)pyrene is due to alterations in accessory cell function. 1988 1
47 3115566 Contrasting disposition and metabolism of topically applied benzo(a)pyrene, trans-7,8-dihydroxy-7,8-dihydrobenzo(a)pyrene, and 7 beta,8 alpha-dihydroxy-9 alpha,10 alpha-epoxy-7,8,9,10-tetrahydrobenzo(a)pyrene in mouse epidermis in vivo. 1987 Oct 15 2
48 3769749 [Micronucleus test in cultured cells--preliminary study]. 1986 Mar 1
49 3975919 Quantitating exposure to chemical carcinogens: in vivo alkylation of hemoglobin by benzo[a]pyrene. 1985 Mar 15 1
50 4061096 Differences in pulmonary metabolism of benzo(a)pyrene in inbred mouse strains, using the isolated perfused lung. 1985 Sep 1