alpha-naphthoflavone

cytochrome P450 family 1 subfamily B member 1 ; Homo sapiens







25 Article(s)
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1 35567365 Design, Synthesis and In Vivo Fluorescence Imaging Study of a Cytochrome P450 1B1 Targeted NIR Probe Containing a Chelator Moiety. 2022 May 14 2
2 33069055 Discovery of heterocycle-containing α-naphthoflavone derivatives as water-soluble, highly potent and selective CYP1B1 inhibitors. 2021 Jan 1 1
3 34455300 α-naphthoflavone-derived cytochrome P450 (CYP)1B1 degraders specific for sensitizing CYP1B1-mediated drug resistance to prostate cancer DU145: Structure activity relationship. 2021 Nov 4
4 34474468 Perspective of structural flexibility on selective inhibition towards CYP1B1 over CYP1A1 by α-naphthoflavone analogs. 2021 Sep 22 3
5 31830634 Synthesis and structure-activity relationship studies of α-naphthoflavone derivatives as CYP1B1 inhibitors. 2020 Feb 1 2
6 31945665 Design and synthesis of α-naphthoflavone chimera derivatives able to eliminate cytochrome P450 (CYP)1B1-mediated drug resistance via targeted CYP1B1 degradation. 2020 Mar 1 4
7 32060993 Inhibition of human CYP1 enzymes by a classical inhibitor α-naphthoflavone and a novel inhibitor N-(3, 5-dichlorophenyl)cyclopropanecarboxamide: An in vitro and in silico study. 2020 May 3
8 32156703 Structure of an ancestral mammalian family 1B1 cytochrome P450 with increased thermostability. 2020 Apr 24 1
9 30553624 Design and synthesis of selective CYP1B1 inhibitor via dearomatization of α-naphthoflavone. 2019 Jan 15 1
10 29152048 Structure-Based Design and Synthesis of New Estrane-Pyridine Derivatives as Cytochrome P450 (CYP) 1B1 Inhibitors. 2017 Nov 9 1
11 27714268 Biphenyl urea derivatives as selective CYP1B1 inhibitors. 2016 Sep 26 2
12 25799264 Design and Synthesis of New α-Naphthoflavones as Cytochrome P450 (CYP) 1B1 Inhibitors To Overcome Docetaxel-Resistance Associated with CYP1B1 Overexpression. 2015 Apr 23 4
13 22511118 CYP1B1 detection. 2012 Feb 1
14 21147782 Structural characterization of the complex between alpha-naphthoflavone and human cytochrome P450 1B1. 2011 Feb 18 3
15 19789301 UVR exposure sensitizes keratinocytes to DNA adduct formation. 2009 Oct 1
16 14962508 A comparative study on the effects of 2,3,7,8,-tetrachlorodibenzo-p-dioxin polychlorinated biphenyl126 and estrogen in human bronchial epithelial cells. 2004 Feb 15 2
17 15280921 Cytochrome P450 CYP1B1 activity in renal cell carcinoma. 2004 Aug 31 1
18 12628515 Cytochrome P450 1B1: a target for inhibition in anticarcinogenesis strategies. 2003 Feb-Mar 1
19 12386117 Docetaxel (Taxotere) is not metabolized by recombinant human CYP1B1 in vitro, but acts as an effector of this isozyme. 2002 Nov 1
20 10534316 Catalysis of drug oxidation during embryogenesis in human hepatic tissues using imipramine as a model substrate. 1999 Nov 1
21 9760279 Selectivity of polycyclic inhibitors for human cytochrome P450s 1A1, 1A2, and 1B1. 1998 Sep 2
22 9354437 Inhibition of human cytochrome P450-catalyzed oxidations of xenobiotics and procarcinogens by synthetic organoselenium compounds. 1997 Nov 1 1
23 6192910 Polycyclic aromatic hydrocarbon toxicity and induction of metabolism in cultivated esophageal and epidermal keratinocytes. 1983 Oct 1
24 6935473 Aryl hydrocarbon hydroxylase in human bronchial epithelium and blood monocyte. 1981 Feb 2
25 5030831 The role of aryl hydrocarbon hydroxylase in 7,12-dimethylbenz(a)anthracene skin tumorigenesis: on the mechanism of 7,8-benzoflavone inhibition of tumorigenesis. 1972 Jun 1