Pub. Date : 2020 Apr 24
PMID : 32156703
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Whereas extant human CYP1B1 has one molecule of alpha-naphthoflavone in a closed active site, we observed that subtle amino acid substitutions outside the active site in the ancestor CYP1B enzyme yielded an open active site with four ligand copies. | alpha-naphthoflavone | cytochrome P450 family 1 subfamily B member 1 | Homo sapiens |