safinamide

monoamine oxidase B ; Homo sapiens







63 Article(s)
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1 34031800 Effects of safinamide on non-motor, cognitive, and behavioral symptoms in fluctuating Parkinson's disease patients: a prospective longitudinal study. 2022 Jan 1
2 34597253 Efficacy and safety evaluation of safinamide as an add-on treatment to levodopa for parkinson's disease. 2022 Feb 1
3 34823038 Long-term changes in short-interval intracortical facilitation modulate motor cortex plasticity and L-dopa-induced dyskinesia in Parkinson's disease. 2022 Jan-Feb 1
4 34990933 Indoles and 1-(3-(benzyloxy)benzyl)piperazines: Reversible and selective monoamine oxidase B inhibitors identified by screening an in-house compound library. 2022 Feb 1
5 35001806 Safinamide protects against amyloid β (Aβ)-induced oxidative stress and cellular senescence in M17 neuronal cells. 2022 Jan 2
6 35107654 A critical appraisal of MAO-B inhibitors in the treatment of Parkinson's disease. 2022 Jun 1
7 35190544 Safinamide in the treatment pathway of Parkinson's Disease: a European Delphi Consensus. 2022 Feb 21 1
8 35596745 Monoamine oxidase binding not expected to significantly affect [18F]flortaucipir PET interpretation. 2022 May 21 2
9 32681474 The tolerability, safety and efficacy of safinamide in elderly Parkinson's disease patients: a retrospective study. 2021 Jun 2
10 33068177 Safinamide improves executive functions in fluctuating Parkinson's disease patients: an exploratory study. 2021 Feb 1
11 33387637 Safinamide in neurological disorders and beyond: Evidence from preclinical and clinical studies. 2021 Mar 1
12 34142645 Switch from rasagiline to safinamide in fluctuating Parkinson's disease patients: a retrospective, pilot study. 2021 Nov 1
13 34162132 Safinamide prevents lipopolysaccharide (LPS)-induced inflammation in macrophages by suppressing TLR4/NF-κB signaling. 2021 Jul 2
14 34390968 Discovery of novel and potent safinamide-based derivatives as highly selective hMAO-B inhibitors for treatment of Parkinson's disease (PD): Design, synthesis, in vitro, in vivo and in silico biological studies. 2021 Oct 3
15 34784871 How to optimize the effectiveness and safety of Parkinson's disease therapy? - a systematic review of drugs interactions with food and dietary supplements. 2021 Nov 16 1
16 34970960 The Role of Monoamine Oxidase B Inhibitors in the Treatment of Parkinson's Disease - An Update. 2021 Dec 31 1
17 32446176 Efficacy and safety of safinamide as an add-on therapy to L-DOPA for patients with Parkinson's disease: A randomized, double-blind, placebo-controlled, phase II/III study. 2020 Jun 2
18 32612042 [Safinamide Mesilate (Equfina® TABLETS 50 mg): preclinical and clinical pharmacodynamics, efficacy, and safety]. 2020 1
19 32648512 Safinamide in the treatment of Parkinson's disease. 2020 Aug 1
20 32673884 Long-term safety and efficacy of safinamide as add-on therapy in levodopa-treated Japanese patients with Parkinson's disease with wearing-off: Results of an open-label study. 2020 Sep 15 1
21 32682215 Neuroprotective and neuro-survival properties of safinamide against methamphetamine-induced neurodegeneration: Hypothetic possible role of BDNF/TrkB/PGC-1α signaling pathway and mitochondrial uncoupling protein -2(UCP-2). 2020 Oct 4
22 30160213 Different Generations of Type-B Monoamine Oxidase Inhibitors in Parkinson's Disease: From Bench to Bedside. 2019 3
23 30919054 Cross-interaction of tau PET tracers with monoamine oxidase B: evidence from in silico modelling and in vivo imaging. 2019 Jun 2
24 29339106 Safinamide: a new hope for Parkinson's disease? 2018 Mar 2
25 29464559 Monoamine Oxidases. 2018 1
26 29542008 Long-term Efficacy of Safinamide on Parkinson's Disease Chronic Pain. 2018 Apr 1
27 29760163 ▼ Safinamide for Parkinson's disease. 2018 May 3
28 30142650 [Effectiveness and safety of safinamide as add-on to levodopa in patients with parkinson's disease: non-interventional study]. 2018 Oct 2
29 30341696 Monoamine oxidase inhibitors, and iron chelators in depressive illness and neurodegenerative diseases. 2018 Nov 1
30 27665574 Clinical Pharmacokinetics and Pharmacodynamics of Safinamide. 2017 Mar 1
31 27855360 Benzyloxynitrostyrene analogues - A novel class of selective and highly potent inhibitors of monoamine oxidase B. 2017 Jan 5 1
32 28110399 Safinamide: A Review in Parkinson's Disease. 2017 Feb 2
33 28537214 Pharmacokinetic drug evaluation of safinamide mesylate for the treatment of mid-to-late stage Parkinson's disease. 2017 Jun 1
34 28682929 Determination of Monoamine Oxidase A and B Activity in Long-Term Treated Patients With Parkinson Disease. 2017 Sep/Oct 2
35 28777756 Long-Term Effects of Safinamide on Mood Fluctuations in Parkinson's Disease. 2017 3
36 29018297 Xadago (Safinamide): A Monoamine Oxidase B Inhibitor for the Adjunct Treatment of Motor Symptoms in Parkinson's Disease. 2017 Oct 4
37 29130466 [Safinamide from daily clinical practice: first clinical steps]. 2017 Nov 16 1
38 26849427 The safety and efficacy of safinamide mesylate for the treatment of Parkinson's disease. 2016 1
39 26917951 Adjuvant therapies for Parkinson's disease: critical evaluation of safinamide. 2016 1
40 27536120 Emerging approaches in Parkinson's disease - adjunctive role of safinamide. 2016 1
41 27803666 Inhibitors of MAO-A and MAO-B in Psychiatry and Neurology. 2016 2
42 26164425 Defining the Role of the Monoamine Oxidase-B Inhibitors for Parkinson's Disease. 2015 Jun 1
43 26293004 New treatments for levodopa-induced motor complications. 2015 Sep 15 1
44 26744740 Safinamide for symptoms of Parkinson's disease. 2015 Nov 1
45 24950010 Treatment of early Parkinson's disease. 2014 Aug 1
46 25342080 Pharmacological strategies for the management of levodopa-induced dyskinesia in patients with Parkinson's disease. 2014 Dec 1
47 23360954 Tremorolytic effects of safinamide in animal models of drug-induced parkinsonian tremor. 2013 Apr 1
48 24053341 Current status of safinamide for the drug portfolio of Parkinson's disease therapy. 2013 Sep 1
49 22948897 The effect of safinamide, a novel drug for Parkinson's disease, on pressor response to oral tyramine: a randomized, double-blind, clinical trial. 2012 Oct 1
50 27186120 Investigational agents in the treatment of Parkinson's disease: focus on safinamide. 2012 1