Pub. Date : 2019
PMID : 30160213
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In contrast, safinamide is a reversible MAOB inhibitor, and also inhibits voltage- sensitive sodium channels and glutamate release. | safinamide | monoamine oxidase B | Homo sapiens |
| 2 | Safinamide is the prototype of a new generation of multi-active MAOB inhibitors, which includes the antiepileptic drug, zonisamide. | safinamide | monoamine oxidase B | Homo sapiens |
| 3 | Among all antiparkinsonian agents, MAOB inhibitors are those with the greatest neuroprotective potential because of inhibition of dopamine metabolism, induction of neurotrophic factors, and, in the case of safinamide, inhibition of glutamate release. | safinamide | monoamine oxidase B | Homo sapiens |