Selegiline

monoamine oxidase B ; Homo sapiens







416 Article(s)
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1 35198978 Characterization of neuroinflammatory positron emission tomography biomarkers in chronic traumatic encephalopathy. 2022 1
2 35447344 The evaluation of N-propargylamine-2-aminotetralin as an inhibitor of monoamine oxidase. 2022 Jul 1 2
3 35587267 Antibody-Mediated Screening of Peptide Inhibitors for Monoamine Oxidase-B (MAO-B) from an Autodisplayed FV Library. 2022 Jun 15 1
4 35624406 Modelling the neurodevelopmental pathogenesis in neuropsychiatric disorders. Bioactive kynurenines and their analogues as neuroprotective agents-in celebration of 80th birthday of Professor Peter Riederer. 2022 Jun 1
5 32476010 Detection of l-Methamphetamine and l-Amphetamine as Selegiline Metabolites. 2021 Feb 6 1
6 33759401 Selegiline reduces daytime sleepiness in patients with Parkinson's disease. 2021 May 1
7 33818516 Evaluation of the combined activity of benzimidazole arylhydrazones as new anti-Parkinsonian agents: monoamine oxidase-B inhibition, neuroprotection and oxidative stress modulation. 2021 Nov 1
8 34290084 Monoamine Oxidase-B Inhibition Facilitates α-Synuclein Secretion In Vitro and Delays Its Aggregation in rAAV-Based Rat Models of Parkinson's Disease. 2021 Sep 1 1
9 34352710 Biphenylpiperazine Based MAO Inhibitors: Synthesis, Biological Evaluation, Reversibility and Molecular Modeling Studies. 2021 Oct 1
10 34553601 Identification of a Chlorogenic Ester as a Monoamine Oxidase (MAO-B) Inhibitor by Integrating "Traditional and Machine Learning" Virtual Screening and In Vitro as well as In Vivo Validation: A Lead against Neurodegenerative Disorders? 2021 Oct 6 1
11 34784871 How to optimize the effectiveness and safety of Parkinson's disease therapy? - a systematic review of drugs interactions with food and dietary supplements. 2021 Nov 16 1
12 34867348 Monoamine Oxidase-B Inhibitor Reduction in Pro-Inflammatory Cytokines Mediated by Inhibition of cAMP-PKA/EPAC Signaling. 2021 1
13 34970960 The Role of Monoamine Oxidase B Inhibitors in the Treatment of Parkinson's Disease - An Update. 2021 Dec 31 1
14 31146671 Design, Synthesis and Evaluation of 8-Thiosubstituted 1,3,7- Trimethylxanthine Hydrazones with In-vitro Neuroprotective and MAO-B Inhibitory Activities. 2020 2
15 31562557 Selegiline: a molecule with innovative potential. 2020 May 2
16 31589885 The pro-psychotic metabotropic glutamate receptor compounds fenobam and AZD9272 share binding sites with monoamine oxidase-B inhibitors in humans. 2020 Jan 1 1
17 32189109 Retraction Note to: Menière's disease: combined pharmacotherapy with betahistine and the MAO-B inhibitor selegiline-an observational study. 2020 Apr 1
18 32858935 Hydride Abstraction as the Rate-Limiting Step of the Irreversible Inhibition of Monoamine Oxidase B by Rasagiline and Selegiline: A Computational Empirical Valence Bond Study. 2020 Aug 26 1
19 33114548 Newly Synthesized Fluorinated Cinnamylpiperazines Possessing Low In Vitro MAO-B Binding. 2020 Oct 26 1
20 30160213 Different Generations of Type-B Monoamine Oxidase Inhibitors in Parkinson's Disease: From Bench to Bedside. 2019 1
21 30857558 Autoradiography validation of novel tau PET tracer [F-18]-MK-6240 on human postmortem brain tissue. 2019 Mar 11 1
22 30906861 Newly developed reversible MAO-B inhibitor circumvents the shortcomings of irreversible inhibitors in Alzheimer's disease. 2019 Mar 1
23 31264403 Computational Insight into the Mechanism of the Irreversible Inhibition of Monoamine Oxidase Enzymes by the Antiparkinsonian Propargylamine Inhibitors Rasagiline and Selegiline. 2019 Aug 21 2
24 29221756 Characterization of the binding site for d-deprenyl in human inflamed synovial membrane. 2018 Feb 1 1
25 29279995 Type A and B monoamine oxidases distinctly modulate signal transduction pathway and gene expression to regulate brain function and survival of neurons. 2018 Nov 2
26 29309800 Partial reversal of the effort-related motivational effects of tetrabenazine with the MAO-B inhibitor deprenyl (selegiline): Implications for treating motivational dysfunctions. 2018 Mar 4
27 29417334 Pharmacological aspects of the neuroprotective effects of irreversible MAO-B inhibitors, selegiline and rasagiline, in Parkinson's disease. 2018 Nov 2
28 29498006 Inhibition of Cyclooxygenase-2 (COX-2) Initiates Autophagy and Potentiates MPTP-Induced Autophagic Cell Death of Human Neuroblastoma Cells, SH-SY5Y: an Inside in the Pathology of Parkinson's Disease. 2018 Oct 2
29 29526790 Selegiline increases on time without exacerbation of dyskinesia in 6-hydroxydopamine-lesioned rats displaying l-Dopa-induced wearing-off and abnormal involuntary movements. 2018 Jul 16 1
30 29532287 Menière's disease: combined pharmacotherapy with betahistine and the MAO-B inhibitor selegiline-an observational study. 2018 Oct 2
31 29671581 Proposing Novel MAO-B Hit Inhibitors Using Multidimensional Molecular Modeling Approaches and Application of Binary QSAR Models for Prediction of Their Therapeutic Activity, Pharmacokinetic and Toxicity Properties. 2018 Jul 18 1
32 29847694 A multiple treatment comparison meta-analysis of monoamine oxidase type B inhibitors for Parkinson's disease. 2018 Sep 3
33 29955193 Interaction between Monoamine Oxidase B Inhibitors and Selective Serotonin Reuptake Inhibitors. 2018 May-Jun 1
34 30016860 Development of Novel Monoamine Oxidase-B (MAO-B) Inhibitors with Reduced Blood-Brain Barrier Permeability for the Potential Management of Noncentral Nervous System (CNS) Diseases. 2018 Aug 23 2
35 30077198 Garcinol, an effective monoamine oxidase-B inhibitor for the treatment of Parkinson's disease. 2018 Aug 1
36 30272370 L‑Deprenyl exerts cytotoxicity towards acute myeloid leukemia through inhibition of mitochondrial respiration. 2018 Dec 2
37 30341696 Monoamine oxidase inhibitors, and iron chelators in depressive illness and neurodegenerative diseases. 2018 Nov 1
38 28108387 Inhibition of monoamine oxidase-B by selegiline reduces cigarette smoke-induced oxidative stress and inflammation in airway epithelial cells. 2017 Feb 15 4
39 28299453 Simultaneous determination of MAO-A and -B activity following first time intake of an irreversible MAO-B inhibitor in patients with Parkinson's disease. 2017 Jun 1
40 28301816 MAO enzymes inhibitory activity of new benzimidazole derivatives including hydrazone and propargyl side chains. 2017 May 5 1
41 28359327 Monoamine oxidase B inhibitor, selegiline, reduces 18F-THK5351 uptake in the human brain. 2017 Mar 31 1
42 28550482 Efficacy of rasagiline and selegiline in Parkinson's disease: a head-to-head 3-year retrospective case-control study. 2017 Jun 2
43 28577058 Type B and A monoamine oxidase and their inhibitors regulate the gene expression of Bcl-2 and neurotrophic factors in human glioblastoma U118MG cells: different signal pathways for neuroprotection by selegiline and rasagiline. 2017 Sep 5
44 28738644 Biosensor for the characterisation of hMAO B inhibitors and the quantification of selegiline. 2017 Nov 1 1
45 29114238 Long-term Monitoring Gait Analysis Using a Wearable Device in Daily Lives of Patients with Parkinson's Disease: The Efficacy of Selegiline Hydrochloride for Gait Disturbance. 2017 1
46 29229003 Comparative binding properties of the tau PET tracers THK5117, THK5351, PBB3, and T807 in postmortem Alzheimer brains. 2017 Dec 11 1
47 25604428 Modulation of monoamine oxidase (MAO) expression in neuropsychiatric disorders: genetic and environmental factors involved in type A MAO expression. 2016 Feb 1
48 26585057 In Vivo and In Vitro Characterization of a Novel MAO-B Inhibitor Radioligand, 18F-Labeled Deuterated Fluorodeprenyl. 2016 Feb 2
49 26590367 The MAO-B inhibitor deprenyl reduces the oral tremor and the dopamine depletion induced by the VMAT-2 inhibitor tetrabenazine. 2016 Feb 1 1
50 26964672 Novel tricyclic pyrazolo[1,5-d][1,4]benzoxazepin-5(6H)-one: Design, synthesis, model and use as hMAO-B inhibitors. 2016 Apr 15 1