Title : The evaluation of N-propargylamine-2-aminotetralin as an inhibitor of monoamine oxidase.

Pub. Date : 2022 Jul 1

PMID : 35447344






2 Functional Relationships(s)
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1 Two propargylamine-containing MAO-B inhibitors, selegiline ((R)-deprenyl) and rasagiline, are currently used in the clinic for this purpose. Selegiline monoamine oxidase B Homo sapiens
2 An important consideration is that selegiline and rasagiline display specificity for MAO-B over the MAO-A isoform thus reducing the risk of tyramine-induced changes in blood-pressure. Selegiline monoamine oxidase B Homo sapiens