Pregnenolone Carbonitrile

cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 ; Rattus norvegicus







19 Article(s)
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1 20551240 Liverbeads: a practical and relevant in vitro model for gene induction investigations. 2010 Sep 1
2 16673044 Cytochrome P4503A: evidence for mRNA expression and catalytic activity in rat brain. 2006 Jul 3
3 15367577 Simultaneous substitution of phenylalanine-305 and aspartate-318 of rat pregnane X receptor with the corresponding human residues abolishes the ability to transactivate the CYP3A23 promoter. 2005 Feb 1
4 15486074 Metabolic activation of fluoropyrrolidine dipeptidyl peptidase-IV inhibitors by rat liver microsomes. 2005 Jan 1
5 15596064 Microarray analysis on CYPs expression in pregnant rats after treatment with pregnenolone-16alpha-carbonitrile and phenobarbital. 2005 Feb 2
6 15826607 Clofibrate and perfluorodecanoate both upregulate the expression of the pregnane X receptor but oppositely affect its ligand-dependent induction on cytochrome P450 3A23. 2005 May 1 2
7 15282211 Desmethoxyyangonin and dihydromethysticin are two major pharmacological kavalactones with marked activity on the induction of CYP3A23. 2004 Nov 2
8 12710709 Induction of CYP3A1 by dexamethasone and pregnenolone-16alpha-carbonitrile in pregnant rat and fetal livers and placenta. 2003 Mar 3
9 12746107 Studies on the induction of rat hepatic CYP1A, CYP2B, CYP3A and CYP4A subfamily form mRNAs in vivo and in vitro using precision-cut rat liver slices. 2003 May 1
10 12877353 In vitro induction of cytochrome P4503A1-mRNA and testosterone hydroxylation in precision-cut liver slices from male and female rats. 2003 Jun 2
11 9448712 Characterization of DNA-binding proteins required for glucocorticoid induction of CYP3A23. 1998 Jan 15 2
12 8700101 Trans-species gene transfer for analysis of glucocorticoid-inducible transcriptional activation of transiently expressed human CYP3A4 and rabbit CYP3A6 in primary cultures of adult rat and rabbit hepatocytes. 1996 Jul 1
13 8863830 Glucocorticoid receptor-independent transcriptional induction of cytochrome P450 3A1 by metyrapone and its potentiation by glucocorticoid. 1996 Oct 1
14 7499421 A novel cis-acting element in a liver cytochrome P450 3A gene confers synergistic induction by glucocorticoids plus antiglucocorticoids. 1995 Dec 1 3
15 7538072 Differential regulation of the cytochrome P450 3A1 gene transcription by dexamethasone in immature and adult rat liver. 1995 Apr 1 1
16 8849332 Distribution and induction of CYP3A1 and CYP3A2 in rat liver and extrahepatic tissues. 1995 Dec 22 2
17 8001226 Involvement of cytochrome P4503A in catalysis of tamoxifen activation and covalent binding to rat and human liver microsomes. 1994 Dec 1
18 7686458 Modulation of rat hepatic CYP3A1 induction by the interferon inducer polyinosinic acid-polycytidylic acid (polyic). 1993 May-Jun 1
19 2787473 Oxidation of midazolam and triazolam by human liver cytochrome P450IIIA4. 1989 Jul 1