Title : Involvement of cytochrome P4503A in catalysis of tamoxifen activation and covalent binding to rat and human liver microsomes.

Pub. Date : 1994 Dec

PMID : 8001226






1 Functional Relationships(s)
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1 Antibodies against rat CYP3A1 strongly inhibited tamoxifen binding to liver microsomes from PCN- and phenobarbital-treated rats, whereas the antibodies anti-CYP2B1/2B2 did not inhibit binding. Pregnenolone Carbonitrile cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 Rattus norvegicus