Heparin

plasminogen activator, tissue type ; Homo sapiens







79 Article(s)
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1 31749252 Bivalirudin during thrombolysis with catheter-directed tPA in a heparin-refractory patient: A case report. 2020 Feb 1
2 20445443 Mechanism of the synergistic effect between oversulfated chondroitin-6-sulfate and lysine or 6-aminohexanoic acid in enhancing the in-vitro activation of glutamic plasminogen by tissue plasminogen activator or urokinase. 2010 Jul 2
3 18301879 Elevated pulmonary dead space and coagulation abnormalities suggest lung microvascular thrombosis in patients undergoing cardiac surgery. 2008 Jul 1
4 18638092 Tissue plasminogen activator as a hemodialysis catheter locking solution. 2008 Jul 1
5 18685430 Effect of oversulfation on the chemical and biological properties of chondroitin-4-sulfate. 2008 Sep 1
6 18976135 The ATTEMPTS delivery systems for macromolecular drugs. 2008 Nov 2
7 16260060 Construction and characterization of a t-PA mutant for use in ATTEMPTS: a drug delivery system for achieving targeted thrombolysis. 2005 Dec 10 3
8 14964479 Intravenous thrombolysis for acute stroke. 2004 Jan 1
9 15726889 Mechanism of the stimulatory effect of native fucoidan, highly sulfated fucoidan and heparin on plasminogen activation by tissue plasminogen activator: the role of chloride. 2004 Oct-Dec 1
10 12679132 Effects of argatroban and heparin on thrombus formation and tissue plasminogen activator-induced thrombolysis in a microvascular thrombosis model. 2003 Jan 1 1
11 11991242 Effects of a low molecular weight heparin, bemiparin, and unfractionated heparin on hemostatic properties of endothelium. 2002 Jan 1
12 12441912 Thrombolytic fibrin specificity influences activated partial thromboplastin time prolongation in vitro. 2002 Dec 1
13 11389993 ATTEMPTS: a heparin/protamine-based prodrug approach for delivery of thrombolytic drugs. 2001 May 14 1
14 12577350 [Clinical observation on effect of intervention therapy with anticoagulant in treating patients of hypertension complicated with acute ischemic cerebrovascular disease]. 2001 Apr 1
15 10756332 A novel heparin/protamine-based pro-drug type delivery system for protease drugs. 2000 May 9
16 10340997 Functionally inactive protein C inhibitor in seminal plasma may be associated with infertility. 1999 Jun 1
17 9453518 Relation of coagulation parameters to patency and recurrent ischemia in the Thrombolysis in Myocardial Infarction (TIMI) Phase II Trial. 1998 Jan 1
18 9626825 Randomized comparison of direct thrombin inhibition versus heparin in conjunction with fibrinolytic therapy for acute myocardial infarction: results from the GUSTO-IIb Trial. Global Use of Strategies to Open Occluded Coronary Arteries in Acute Coronary Syndromes (GUSTO-IIb) Investigators. 1998 Jun 2
19 9664197 Reperfusion therapy for acute myocardial infarction. Which strategy for which patient? 1998 Jul 1
20 10608050 A Randomized, Blinded Study of Two Doses of Novastan(R) (Brand of Argatroban) Versus Heparin as Adjunctive Therapy to Recombinant Tissue Plasminogen Activator (Accelerated Administration) in Acute Myocardial Infarction: Rationale and Design of the Myocardial Infarction using Novastan(R) and T-PA (MINT) Study. 1998 1
21 9140688 Is heparin of value in the management of acute myocardial infarction? 1997 Apr 1
22 9241751 Effects of heparin therapy on fibrinolysis in patients with pulmonary embolism. 1997 Jun 1
23 9307014 Heparin inhibits the binding of basic fibroblast growth factor to cultured human aortic smooth-muscle cells. 1997 Sep 15 1
24 8623729 A randomized factorial trial of reperfusion strategies and aspirin dosing in acute myocardial infarction. The DUCCS-II Investigators. 1996 Apr 15 1
25 8739535 Physical and pharmacologic manipulation of the vascular system as measured by the release of TFPI and other mediators of antithrombotic actions. 1996 Mar 1
26 8874867 Interaction of reteplase with heparin. A comparison between reteplase and alteplase. 1996 Jul 8
27 8909909 ESPRIT: a European study of the prevention of reocclusion after initial thrombolysis with duteplase in acute myocardial infarction. 1996 Oct 1
28 8925311 [Adjuvant therapy in patients with acute myocardial infarct]. 1996 Jul 1
29 8963700 [Antithrombotic therapy in acute myocardial infarct]. 1996 Aug 1
30 10602554 Enhancing Thrombolysis with Adjunctive Therapy. 1996 1
31 7481155 [Myocardial infarction and revascularization. Current indications]. 1995 1
32 7588083 Alteplase. A reappraisal of its pharmacological properties and therapeutic use in acute myocardial infarction. 1995 Jul 1
33 7731256 Adjunctive therapy in the management of patients with acute myocardial infarction. 1995 May 1
34 10172669 Alteplase: a pharmacoeconomic evaluation of its use in the management of myocardial infarction. 1995 Nov 1
35 7807964 Heparin selectively inhibits synthesis of tissue type plasminogen activator and matrix deposition of plasminogen activator inhibitor 1 by human mesangial cells. 1994 Dec 3
36 7863705 [Different therapeutic regimens in thrombolysis of acute myocardial infarct]. 1994 1
37 7921367 The role of thrombolytic therapy for acute myocardial infarction. 1994 May 1
38 7952425 Lack of degradation of antithrombin III by tissue-type plasminogen activator or plasmin. 1994 Jul 2
39 8016815 Effects of heparan sulfate analogue or other sulfated polysaccharides on the activation of plasminogen by t-PA or u-PA. 1994 Mar 1 1
40 8034236 Effect of low-dose heparin treatment on fibrinolysis in patients with previous myocardial infarction. 1993 Nov-Dec 4
41 8128448 Interaction of plasminogen activators and plasminogen with heparin: effect of ionic strength. 1993 Nov 15 3
42 8261475 The challenge of maintaining coronary arterial patency with intravenous heparin following tissue plasminogen activator administration. 1993 1
43 8292721 Effects of low molecular weight heparins on fibrin polymerization and clot sensitivity to t-PA-induced lysis. 1993 Oct 4
44 1280862 Influence of heparin and a low molecular weight heparinoid on specific endogenous and exogenous fibrinolytic factors during rest and exercise. 1992 Nov 10 1
45 1520875 Heparin enhances active site-dependent binding of tissue-type plasminogen activator to endothelial cells. 1992 Sep 15 1
46 1643205 Fibrin clots obtained from plasma containing heparin show a higher sensitivity to t-PA-induced lysis. 1992 Jun 4
47 1728444 Thrombolysis in unstable angina. Randomized double-blind trial of t-PA and placebo. 1992 Jan 1
48 1661447 Standard heparin but not LMW heparin induces a concomitant increase of t-PA and PAI-1 without modification of global fibrinolysis: study after 60 days treatment. 1991 Sep 1 1
49 1708387 The inhibition of tissue type plasminogen activator by plasminogen activator inhibitor-1. The effects of fibrinogen, heparin, vitronectin, and lipoprotein(a). 1991 Apr 25 3
50 1850874 The initial release of t-PA induced by dDAVP is more important with low molecular weight heparin than with unfractionated heparin. 1991 Jan 23 2