| 1 |
33664850 | Vitamin C activates pyruvate dehydrogenase (PDH) targeting the mitochondrial tricarboxylic acid (TCA) cycle in hypoxic KRAS mutant colon cancer. | 2021 |
4 |
| 2 |
33725483 | Rheb mediates neuronal-activity-induced mitochondrial energetics through mTORC1-independent PDH activation. | 2021 Mar 22 |
2 |
| 3 |
33860280 | Isotope tracing reveals glycolysis and oxidative metabolism in childhood tumors of multiple histologies. | 2021 Apr 9 |
3 |
| 4 |
34375613 | The requirement for pyruvate dehydrogenase in leukemogenesis depends on cell lineage. | 2021 Sep 7 |
2 |
| 5 |
34679752 | FRI-1 Is an Anti-Cancer Isoquinolinequinone That Inhibits the Mitochondrial Bioenergetics and Blocks Metabolic Shifts by Redox Disruption in Breast Cancer Cells. | 2021 Oct 14 |
2 |
| 6 |
31828927 | miR-128-3p contributes to mitochondrial dysfunction and induces apoptosis in glioma cells via targeting pyruvate dehydrogenase kinase 1. | 2020 Mar |
1 |
| 7 |
31857147 | Epigallocatechin-3-gallate downregulates PDHA1 interfering the metabolic pathways in human herpesvirus 8 harboring primary effusion lymphoma cells. | 2020 Jun |
2 |
| 8 |
32033248 | A Dietary Ketone Ester Normalizes Abnormal Behavior in a Mouse Model of Alzheimer's Disease. | 2020 Feb 4 |
4 |
| 9 |
32319629 | Conditional knockout of pyruvate dehydrogenase in mouse pancreatic β‑cells causes morphological and functional changes. | 2020 Apr |
1 |
| 10 |
31623369 | Differential Mechanism of ATP Production Occurs in Response to Succinylacetone in Colon Cancer Cells. | 2019 Oct 3 |
2 |
| 11 |
29134060 | Modelling pyruvate dehydrogenase under hypoxia and its role in cancer metabolism. | 2017 Oct |
2 |
| 12 |
27621446 | E4F1 controls a transcriptional program essential for pyruvate dehydrogenase activity. | 2016 Sep 27 |
2 |
| 13 |
25277736 | Effect of high-fat and high-carbohydrate diets on pulmonary O2 uptake kinetics during the transition to moderate-intensity exercise. | 2014 Dec 1 |
1 |
| 14 |
25458843 | Regulation of substrate utilization by the mitochondrial pyruvate carrier. | 2014 Nov 6 |
2 |
| 15 |
25517164 | A pH-dependent kinetic model of dihydrolipoamide dehydrogenase from multiple organisms. | 2014 Dec 16 |
2 |
| 16 |
23247844 | FOXO1-mediated upregulation of pyruvate dehydrogenase kinase-4 (PDK4) decreases glucose oxidation and impairs right ventricular function in pulmonary hypertension: therapeutic benefits of dichloroacetate. | 2013 Mar |
4 |
| 17 |
22508045 | Influence of dichloroacetate (DCA) on lactate production and oxygen consumption in neuroblastoma cells: is DCA a suitable drug for neuroblastoma therapy? | 2012 |
2 |
| 18 |
23028062 | Estrogen modulates metabolic pathway adaptation to available glucose in breast cancer cells. | 2012 Dec |
2 |
| 19 |
21596918 | The relationship between human skeletal muscle pyruvate dehydrogenase phosphatase activity and muscle aerobic capacity. | 2011 Aug |
2 |
| 20 |
21820830 | Astrocytic energy metabolism and glutamate formation--relevance for 13C-NMR spectroscopy and importance of cytosolic/mitochondrial trafficking. | 2011 Dec |
3 |
| 21 |
19639391 | A cognitively normal PDH-deficient 18-year-old man carrying the R263G mutation in the PDHA1 gene. | 2009 Dec |
2 |
| 22 |
11991544 | Regulation of pyruvate dehydrogenase (PDH) activity in human skeletal muscle during exercise. | 2002 Apr |
1 |
| 23 |
2376596 | Characterization of two cDNA clones for pyruvate dehydrogenase E1 beta subunit and its regulation in tricarboxylic acid cycle-deficient fibroblast. | 1990 Aug 5 |
2 |