Cholic Acid

cytochrome P450 family 8 subfamily B member 1 ; Homo sapiens







15 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 34411400 Bile acid dysmetabolism in the gut-microbiota-liver axis under hepatitis C virus infection. 2022 Jan 2
2 30465713 Conversion of chenodeoxycholic acid to cholic acid by human CYP8B1. 2019 Apr 24 2
3 31372666 Signatures of Relaxed Selection in the CYP8B1 Gene of Birds and Mammals. 2019 Sep 1
4 30232649 Rethinking Bile Acid Metabolism and Signaling for Type 2 Diabetes Treatment. 2018 Sep 19 1
5 30399365 Chemical synthesis of 7-oxygenated 12α-hydroxy steroid derivatives to enable the biochemical characterization of cytochrome P450 8B1, the oxysterol 12α-hydroxylase enzyme implicated in cardiovascular health and obesity. 2018 Dec 1
6 22111624 Cytochrome P450s in the synthesis of cholesterol and bile acids--from mouse models to human diseases. 2012 May 1
7 17346171 Enzymes in the conversion of cholesterol into bile acids. 2007 Mar 1
8 17585019 Human and murine hepatic sterol-12-alpha-hydroxylase and other xenobiotic metabolism mRNA are upregulated by soy isoflavones. 2007 Jul 1
9 15550563 Cytokine regulation of human sterol 12alpha-hydroxylase (CYP8B1) gene. 2005 Apr 2
10 11741989 Differential effects of sterol regulatory binding proteins 1 and 2 on sterol 12 alpha-hydroxylase. SREBP-2 suppresses the sterol 12 alpha-hydroxylase promoter. 2002 Feb 22 1
11 11535594 Transcriptional regulation of the human sterol 12alpha-hydroxylase gene (CYP8B1): roles of heaptocyte nuclear factor 4alpha in mediating bile acid repression. 2001 Nov 9 2
12 11574686 Suppression of sterol 12alpha-hydroxylase transcription by the short heterodimer partner: insights into the repression mechanism. 2001 Oct 1 2
13 10747975 Alpha 1-fetoprotein transcription factor is required for the expression of sterol 12alpha -hydroxylase, the specific enzyme for cholic acid synthesis. Potential role in the bile acid-mediated regulation of gene transcription. 2000 Jun 9 3
14 10051404 Structure and chromosomal assignment of the sterol 12alpha-hydroxylase gene (CYP8B1) in human and mouse: eukaryotic cytochrome P-450 gene devoid of introns. 1999 Mar 1 2
15 9450986 Regulation of bile acid synthesis. 1998 Feb 15 2