Title : Cytochrome P450s in the synthesis of cholesterol and bile acids--from mouse models to human diseases.

Pub. Date : 2012 May

PMID : 22111624






1 Functional Relationships(s)
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1 Disruption of Cyp8b1 from an alternative bile acid pathway results in the absence of cholic acid and a reduced absorption of dietary lipids; however, the human CYP8B1 polymorphism fails to explain differences in bile acid composition. Cholic Acid cytochrome P450 family 8 subfamily B member 1 Homo sapiens