| 1 |
34099595 | A Newly Synthesized Flavone from Luteolin Escapes from COMT-Catalyzed Methylation and Inhibits Lipopolysaccharide-Induced Inflammation in RAW264.7 Macrophages via JNK, p38 and NF-κB Signaling Pathways. | 2022 Jan 28 |
2 |
| 2 |
33389924 | Investigation of Catechol-O-methyltransferase (COMT) gene Val158Met polymorphism in ovarian cancer | 2021 Feb 24 |
3 |
| 3 |
33717608 | Analytical methodologies for sensing catechol-O-methyltransferase activity and their applications. | 2021 Feb |
5 |
| 4 |
33932529 | Discovery and characterization of flavonoids in vine tea as catechol-O-methyltransferase inhibitors. | 2021 Jul |
1 |
| 5 |
34027136 | Interaction of silver nanoparticles with catechol O-methyltransferase: Spectroscopic and simulation analyses. | 2021 Jul |
2 |
| 6 |
34587154 | Suppressor effect of catechol-O-methyltransferase gene in prostate cancer. | 2021 |
2 |
| 7 |
34683865 | Variants in COMT, CYP3A5, CYP2B6, and ABCG2 Alter Quetiapine Pharmacokinetics. | 2021 Sep 28 |
1 |
| 8 |
31586564 | The potential impact of COMT gene variants on dopamine regulation and phenotypic traits of ASD patients. | 2020 Jan 27 |
2 |
| 9 |
31708229 | Neurological and psychiatric management using COMT inhibitors: A review. | 2020 Jan |
1 |
| 10 |
31744341 | Cheminformatics and virtual screening studies of COMT inhibitors as potential Parkinson's disease therapeutics. | 2020 Jan |
2 |
| 11 |
32100171 | Chronic persistent surgical pain is strongly associated with COMT alleles in patients undergoing cardiac surgery with median sternotomy. | 2020 Oct |
2 |
| 12 |
32101397 | Partitioning of Catechol Derivatives in Lipid Membranes: Implications for Substrate Specificity to Catechol-O-methyltransferase. | 2020 Mar 18 |
1 |
| 13 |
32236879 | In Silico Prediction of the Effects of Nonsynonymous Single Nucleotide Polymorphisms in the Human Catechol-O-Methyltransferase (COMT) Gene. | 2020 Jun |
2 |
| 14 |
32492152 | Nano-second protein dynamics of key residue at Position 38 in catechol-O-methyltransferase system: a time-resolved fluorescence study. | 2020 Oct 1 |
1 |
| 15 |
32866920 | Accurate and sensitive detection of Catechol-O-methyltransferase activity by liquid chromatography with fluorescence detection. | 2020 Nov 10 |
1 |
| 16 |
30935952 | The extra virgin olive oil phenolic oleacein is a dual substrate-inhibitor of catechol-O-methyltransferase. | 2019 Jun |
3 |
| 17 |
31080692 | Equatorial Active Site Compaction and Electrostatic Reorganization in Catechol-O-methyltransferase. | 2019 May 3 |
1 |
| 18 |
29168878 | Quercetin and fisetin enhanced the small intestine cellular uptake and plasma levels of epi-catechins in in vitro and in vivo models. | 2018 Jan 24 |
2 |
| 19 |
29410835 | In vitro evaluation of the effect of C-4 substitution on methylation of 7,8-dihydroxycoumarin: metabolic profile and catalytic kinetics. | 2018 Jan |
2 |
| 20 |
29436602 | The expression and activation of sex steroid receptors in the preeclamptic placenta. | 2018 May |
1 |
| 21 |
29654831 | Fingolimod interrupts the cross talk between estrogen metabolism and sphingolipid metabolism within prostate cancer cells. | 2018 Jul |
1 |
| 22 |
30218069 | Catechol-O-methyltransferase (COMT) genotypes are associated with varying soluble, but not membrane-bound COMT protein in the human prefrontal cortex. | 2018 Dec |
2 |
| 23 |
30272964 | Optimization of 8-Hydroxyquinolines as Inhibitors of Catechol O-Methyltransferase. | 2018 Nov 8 |
1 |
| 24 |
27826992 | The Val158Met polymorphism in COMT gene and cancer risk: role of endogenous and exogenous catechols. | 2017 Feb |
8 |
| 25 |
27939670 | Identification and characterization of a catechol-o-methyltransferase cDNA in the catfish Heteropneustes fossilis: Tissue, sex and seasonal variations, and effects of gonadotropin and 2-hydroxyestradiol-17β on mRNA expression. | 2017 May 15 |
2 |
| 26 |
27981425 | 1H, 15N, 13C backbone resonance assignments of human soluble catechol O-methyltransferase in complex with S-adenosyl-L-methionine and 3,5-dinitrocatechol. | 2017 Apr |
2 |
| 27 |
28456872 | Catechol-O-Methyltransferase (COMT): An Update on Its Role in Cancer, Neurological and Cardiovascular Diseases. | 2017 |
2 |
| 28 |
28473194 | Association of Catechol-O-methyltransferase polymorphism Val158Met and mammographic density: A meta-analysis. | 2017 Aug 15 |
1 |
| 29 |
28968204 | Prevalence of COMT Val158Met polymorphism in Eastern UP population. | 2017 Jul 31 |
3 |
| 30 |
26867114 | An Enzyme Cascade for Selective Modification of Tyrosine Residues in Structurally Diverse Peptides and Proteins. | 2016 Mar 9 |
1 |
| 31 |
25159108 | Mechanisms of estrogen carcinogenesis: The role of E2/E1-quinone metabolites suggests new approaches to preventive intervention--A review. | 2015 Jul |
2 |
| 32 |
25815153 | Synthesis and Evaluation of Heterocyclic Catechol Mimics as Inhibitors of Catechol-O-methyltransferase (COMT). | 2015 Mar 12 |
2 |
| 33 |
25084335 | Mapping the conformational space accessible to catechol-O-methyltransferase. | 2014 Aug |
1 |
| 34 |
22124994 | Catechol-O-methyltransferase Val 108/158 Met polymorphism and breast cancer risk: a case control study in Syria. | 2013 Jan |
2 |
| 35 |
23558779 | Catechol metabolites of the mycotoxin zearalenone are poor substrates but potent inhibitors of catechol-O-methyltransferase. | 2013 Aug |
7 |
| 36 |
24141029 | The role of catechol-O-methyltransferase in catechol-enhanced erythroid differentiation of K562 cells. | 2013 Dec 15 |
10 |
| 37 |
24390993 | Contribution of catechol-O-methyltransferase Val158Met polymorphism to endometrial cancer risk in postmenopausal women: a meta-analysis. | 2013 Dec 10 |
3 |
| 38 |
21397529 | Associations differ by sex for catechol-O-methyltransferase genotypes and bladder cancer risk in South Egypt. | 2012 Nov-Dec |
2 |
| 39 |
22129592 | Defining the role of echinocandin catechol functional groups in the development of secondary hepatocellular carcinoma. | 2012 Feb |
3 |
| 40 |
22285433 | Catechol metabolites of zeranol and 17β-estradiol: a comparative in vitro study on the induction of oxidative DNA damage and methylation by catechol-O-methyltransferase. | 2012 Apr 5 |
4 |
| 41 |
22483290 | Inhibitors of Catechol-O-Methyltransferase. | 2012 May |
1 |
| 42 |
22500608 | Serotonin-induced hypersensitivity via inhibition of catechol O-methyltransferase activity. | 2012 Apr 13 |
3 |
| 43 |
23606198 | Genotoxicity and inactivation of catechol metabolites of the mycotoxin zearalenone. | 2012 Nov |
1 |
| 44 |
21538606 | Molecular recognition at the active site of catechol-O-methyltransferase (COMT): adenine replacements in bisubstrate inhibitors. | 2011 May 27 |
1 |
| 45 |
21695287 | COMT genetic variants and pain. | 2011 Jun |
2 |
| 46 |
21731105 | Regioselectivity of Catechol O-Methyltransferase Confers Enhancement of Catalytic Activity. | 2011 Apr 20 |
2 |
| 47 |
21769726 | Importance of the COMT gene for sex differences in brain function and predisposition to psychiatric disorders. | 2011 |
1 |
| 48 |
20336436 | Assessing potential functionality of catechol-O-methyltransferase (COMT) polymorphisms associated with pain sensitivity and temporomandibular joint disorders. | 2010 |
2 |
| 49 |
20606002 | O-methylation of catechol estrogens by human placental catechol-o-methyltransferase: interindividual differences in sensitivity to heat inactivation and to inhibition by dietary polyphenols. | 2010 Oct |
3 |
| 50 |
20659173 | Comt1 genotype and expression predicts anxiety and nociceptive sensitivity in inbred strains of mice. | 2010 Nov |
1 |