Title : Discovery and characterization of flavonoids in vine tea as catechol-O-methyltransferase inhibitors.

Pub. Date : 2021 Jul

PMID : 33932529






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1 Collectively, our findings not only suggested that the strong hCOMT inhibition of vine tea has guiding significance in the drug exposure of catechol drugs, but also identified a promising lead compound for developing more efficacious hCOMT inhibitors. catechol catechol-O-methyltransferase Homo sapiens