Carbidopa

catechol-O-methyltransferase ; Homo sapiens







16 Article(s)
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Pub. Year
#Total Relationships
1 24770794 Fewer fluctuations, higher maximum concentration and better motor response of levodopa with catechol-O-methyltransferase inhibition. 2014 Nov 1
2 22136163 Levodopa infusion combined with entacapone or tolcapone in Parkinson disease: a pilot trial. 2012 Jun 1
3 20077469 The effect of peripheral enzyme inhibitors on levodopa concentrations in blood and CSF. 2010 Feb 15 1
4 19922897 Pharmacokinetic-pharmacodynamic interaction between nebicapone and controlled-release levodopa/benserazide: a single-center, Phase I, double-blind, randomized, placebo-controlled, four-way crossover study in healthy subjects. 2009 Oct 1
5 17948613 Understanding Parkinson's disease: an update on current diagnostic and treatment strategies. 2006 Sep 2
6 15090932 Pharmacokinetic-pharmacodynamic interaction between BIA 3-202, a novel COMT inhibitor, and levodopa/carbidopa. 2004 Jan-Feb 2
7 10882160 Clinical pharmacology, therapeutic use and potential of COMT inhibitors in Parkinson's disease. 2000 Jun 2
8 10981253 Entacapone. 2000 Sep 1
9 11147508 Effect of COMT inhibition on the pharmacokinetics and pharmacodynamics of levodopa in parkinsonian patients. 2000 2
10 10510160 COMT inhibition with tolcapone does not affect carbidopa pharmacokinetics in parkinsonian patients in levodopa/carbidopa (Sinemet). 1999 Sep 1
11 9403227 Effect of tolcapone on plasma levodopa concentrations after coadministration with levodopa/carbidopa to healthy volunteers. 1997 Dec 1
12 8665546 Acute effects of COMT inhibition on L-DOPA pharmacokinetics in patients treated with carbidopa and selegiline. 1995 Aug 1
13 8787797 Pharmacokinetic model of oral levodopa and role of carbidopa in parkinsonian patients. 1995 Dec 1
14 8255478 Catechol-O-methyltransferase inhibitor tolcapone prolongs levodopa/carbidopa action in parkinsonian patients. 1993 Dec 1
15 3111485 Altered metabolism of [18F]-6-fluorodopa in the hooded rat following inhibition of catechol-O-methyltransferase with U-0521. 1987 Aug 1 1
16 7447951 Benserazide and carbidopa as substrates of catechol-O-methyltransferase: new mechanism of action in Parkinson's disease. 1980 Dec 1 1