monophosphate

uridine monophosphate synthetase ; Homo sapiens







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1 22730407 Introduction of a fluorine atom at C3 of 3-deazauridine shifts its antimetabolic activity from inhibition of CTP synthetase to inhibition of orotidylate decarboxylase, an early event in the de novo pyrimidine nucleotide biosynthesis pathway. 2012 Aug 31 1